目的对比多田公式和近似台体体积计算法(PLVCA)测量垂体腺瘤体积的准确性及实用性。方法选择南京军区福州总医院神经外科自2013年5月至2014年5月收治的45例垂体腺瘤患者,根据其MRj图像分为形态规则组和不规则组,分别以虚拟现实(VRl技术重建法、PLVCA法及多田公式测量2组垂体腺瘤的体积,以VR法所得肿瘤体积为标准,比较PLVCA法及多田公式测量垂体腺瘤体积的准确性。结果本组垂体腺瘤中形态规则型17例。与VR法所得肿瘤体积[(9.14±8.46)cm^3]比较,PLVCA法[(7.76±7.45)cm^3]和多田公式[(7.06±7.04)cm^3]测得肿瘤体积比较差异无统计学意义(P〉0.05)。形态不规则型垂体腺瘤28例中,与VR法[(27.75±32.15)cm^3]PLVCA法[(23.89±29.64)cm^3]比较,多田公式[(37.42±43.66)cm^3]测得肿瘤体积较大,差异有统计学意义(P〈0.05),而VR法、PLVCA法测得肿瘤体积比较差异无统计学意义(P〉0.05)。结论在形态不规则的垂体腺瘤的体积测量中,PLVCA法比多田公式具有较高的准确性。
Objective To investigate the accuracy of volumetric measurements (Dotian formula and platform-like volume calculation formula [PLVCA]) in pituitary adenomas and their practicabilities. Methods Forty-five large and giant pituitary adenomas patients, admitted to our hospital from May 2013 to May 2014, were collected. According to the imaging finds of pituitary adenomas, the patients were divided into regular type group and irregular type group; the volume of these tumors were calculated by PLVCA method, Dotian formula and virtual reality (VR) reconstruction method, respectively. The results of VR method were used as the standards to investigate the accuracy of Dotian formula and PLVCA method on pituitary adenomas. Results In 45 pituitary adenomas, 17 (37.78%) were regular; the result of tumor volume using VR method was (6.54±11.27) cm^3, that using PLVCA method was (5.50±9.40) cm^3 and that using Dotian formula was (4.32±9.00) cm^3; significant differences were noted between the results of VR method and PLVCA method and the results of VR method and Dotian formula (P〈0.05); there was no significant difference between the results of PLVCA method and Dorian formula (P〉0.05). Another 28 (62.22%) were irregular; the result of volume using VR method was (11.65±16.60) cm^3, that using PLVCA method was (11.50±16.18) cm^3, there was no significant difference between the two results (P〉0.05); that using Dotian formula was (10.04±19.45) cm^3, and there was significant difference between the VR method and Dotan formula (P〈0.05), which was also found between PLVCA method and Tada formula (P〈0.05). Conclusion PLVCA method has a higher accuracy in volume measurement of pituitary adenomas than Dotian formula, especially in irregular adenomas.