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中文摘要：
为了阐明铜的长期作用对生物体生存状况和生理特性的影响，本文以秀丽小杆线虫Caenorhabditis elegans为材料，在培养基中加入一定浓度的铜（CuSO4·5H2O），最终得到具有Cu^2＋耐性的线虫（TT），其繁殖率显著降低，丙二醛（MDA）含量显著升高，超氧化物歧化酶（SOD）和谷胱甘肽硫转移酶（GST）比活性显著降低，与重金属络合能力强的柠檬酸含量则显著升高。
英文摘要：
In order to clarify the long-term effects of copper on organisms living conditions and physical characteristics, the Caenorhabditis elegans was treated by adding a certain concentration of Cu （ CuSO4· 5 H2O） , and at last, the nematode with one strong tolerance to Cu were got. The reproductivity of this kind of nematode was significantly reduced, malonic dialdehyde（MDA） was significantly increased, superoxide dismutase （SOD） and glutathione S-transferase （GST） activity significantly reduced, and citric acid which could chelate heavy metal to complexity was significantly increased.
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Comparative Studies of Substrate and Inhibitor Specificity of Glutathione STransferases in Six Tissu
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