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中文摘要：
背景：针对现有材料存在的问题,课题组制备了淀粉/聚乙烯醇膜,研究其性能是否满足引导组织再生膜的要求。前期实验已经探讨制备工艺条件对膜性能的影响。目的：观察在最佳的制备工艺条件下淀粉/聚乙烯醇膜的断面结构、生物相容性和体外降解等相关性能。方法：采用溶液浇注,冷冻干燥的方法制备了可降解的多孔淀粉/聚乙烯醇膜。对在预冻温度为-30℃,溶液浓度为5%,聚乙烯醇和淀粉质量比分别为4：1和1：1时制备的淀粉/聚乙烯醇膜的性能进行表征。结果与结论：在淀粉/聚乙烯醇膜的内部都形成了相互关联的孔结构,质量比为1：1的淀粉/聚乙烯醇膜的孔径大于质量比为4：1淀粉/聚乙烯醇膜,L929细胞和MC3T3细胞都能在材料表面黏附生长,并且由于两种膜的降解速率不同,可以根据不同组织的修复速率调节淀粉/聚乙烯醇膜的降解速率,以满足组织的修复需要。
英文摘要：
BACKGROUND：The starch/polyvinyl alcohol（PVA） membrane was prepared to verify whether its property can meet the requirements of guided tissue regeneration membrane.Previous experiments have investigated the influence of preparation techniques on membrane performance.OBJECTIVE：To observe the cross-section structure,biocompatibility and in vitro degradation of the starch/PVA membrane at the optimal preparation conditions.METHODS：Biodegradable and porous starch/PVA membrane was prepared by solution casting and freeze-dried.At pre-freezing temperature-30 ℃ and the solution concentration 5%,PVA and starch mass ratio of 4：1 and 1：1,respectively,the prepared starch/PVA membrane was determined.RESULTS AND CONCLUSION：The interconnected porous structure was formed in the starch/PVA membrane,the pore size of starch/PVA membrane at 1：1 ratio was greater than that at 4：1.Both L929 cells and MC3T3 cells could grow in the membrane surface.The degradation rate of starch/PVA membrane can be regulated by the repairing rate of different tissues to meet the repair requirement.
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