叔丁氧羰基(Boc)作为氨基的重要保护基团在有机合成中已有广泛应用,其脱保护反应的研究不仅决定了合成的成败,而且也会影响反应能否继续进行,因此是合成反应中及其重要的环节。本文综合实例,介绍了N—Boc基团脱保护反应的原理与具体方法。
The amino protective group Boc has been widely used in organic synthesis and the research of deprotection influence not only the synthesis of success, but also the whole reaction. So deprotection is greatly important. This paper studys the Mechanisms and Methods of Deprotection of N-Boc.