进行数量性状基因作图时,需根据侧连标记基因型推断与之相邻的QTL基因型的条件概率.该文首先就该问题对两向、四向杂交分离群体进行了综述.而后针对所述群体的局限性提出了一种新型的八向杂交设计,并推导出其两点概率转移矩阵及以之进行QTL基因型多点联合推断的方法.
The conditional probabilities of QTL genotypes under flanking marker genotypes were needed in QTL mapping. This issue was reviewed in F2 and FW population respectively. And then a new eight-way cross design was proposed, and the two-locus probabilities transition matrix of this design and the method for multi-point joint inference of QTL genotype were educed.