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中药补骨脂化学成分的研究
  • 期刊名称：中药补骨脂化学成分的研究，刘桦，白焱晶，陈亚云，赵玉英，中国中药杂志，2008，33（12）:141
  • 时间：0
  • 分类：R284.1[医药卫生—中药学;医药卫生—中医学]
  • 作者机构：[1]北京大学医学部药学院天然药物学系天然药物及仿生药物国家重点实验室,北京100083
  • 相关基金：国家自然科学基金重点项目（20432030）;长江学者和创新团队计划项目（985-2-063-112）
  • 相关项目：高效快速新颖结构天然产物的发现及其生物活性研究
关键词： 补骨脂, 呋喃(2″, 3″, 7, 6)-4′-羟基二氢黄酮, 补骨脂二氢黄酮, 香豆苯醚, Psoralea corylifolia , furano （ 2＂, 3＂, 7, 6） -4′-hydroxyflavanone, psoraleflavanone, coumastans
中文摘要：

目的：研究中药补骨脂的化学成分。方法：用色谱分离，用理化性质及波谱方法鉴定结构。结果：从中分离鉴定了5个化合物，分别为呋喃（2″，3″，7，6）-4′-羟基二氢黄酮（1），补骨脂定（2），5，7，4′-三羟基异黄酮（3），补骨脂素（4），异补骨脂素（5）。结论：化合物1为新化合物，命名其为补骨脂二氢黄酮；首次归属了化合物2的^13C—NMR数据。

英文摘要：

Objective： To study the chemical constituents of Psoralea corylifolia. Method： Chromatographic methods were used to separate compounds, and spectroscopic methods were used to determine the structures. Result： Five compounds were isolated and identified as furano （2＂, 3＂, 7, 6） -4′-hydroxyflavanone （ 1 ）, psoralidin （2）, genistein （3）, psoralen （4）, isopsoralen （5）. Conclusion： Compounds 1 was a new compound named psoraleflavanone. And ^13C-NMR data of compound 2 were assined for the first time.

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高效快速新颖结构天然产物的发现及其生物活性研究
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