阿尔茨海默病越来越成为困扰老年人健康的一种疾病,其发生与遗传因素有关,也与以铝为代表的环境因素有关。揭示铝与遗传因素在阿尔茨海默病发生中的作用,对于阐明病因,采取更为有效的预防和治疗方法具有重要意义。本文基于本课题组研究成果并结合现有研究结果进行概述,以便于为阿尔茨海默病的研究提供科学资料。
Alzheimer's disease (AD)is a frequently occurred disease among senior people, the pathogenesis of which is concerned with both genetic factors and environmental factors,in particular aluminum (AI). Studies uncovering the roles of A1 and genetic factors in AD are essential to clarify the pathogenesis and to provide preventive measures. The review is based on the findings of our group and will provide scientific clues for future researches on AD.