中文摘要：

试图调查化学成分和他们大戟属植物 tibetica 的天线部分的生物活动。方法混合物被各种各样的色析法的方法，和他们的结构孤立并且净化包括 2D-NMR 通过广泛的分光镜的技术的使用被阐明，混合物的结构 5 和 6 被单个水晶的 X 光检查晶体学证实。所有孤立的混合物的 Bioactivities 被 MTT 方法在 A549 和 anti-angiogenesis 试金上评估。结果一新混合物，甲基 4-epi-shikimate-3-O-gallate (1 ) ，和 23，已知的成分(224 ) 从 E 的天线部分被孤立。tibetica。结论化合物 1 是新的，并且另外的混合物第一次从这植物被孤立。5， 7， 12， 13， 17 和 19 显示出的 anti-angiogenic 在 zebrafish 完成的人的肺癌症房间 A549 和混合物的生长上的 57， 9， 11， 17， 18 和 20 展出禁止的效果建模的混合物。

英文摘要：

AIM： To investigate the chemical constituents and their biological activities of the aerial parts of Euphorbia tibetica. METHOD： Compounds were isolated and purified by various chromatographic methods, and their structures were elucidated through the use of extensive spectroscopic techniques including 2D-NMR, the structures of compounds 5 and 6 were confirmed by single-crystal X-ray crystallography. Bioactivities of all the isolated compounds were evaluated by the MTT method on A549 and anti-angiogenesis assay. RESULTS： One new compound, methyl 4-epi-shikimate-3-O-gallate （1）, together with twenty-three known constituents （2-24） were isolated from the aerial parts ofE. tibetica. CONCLUSION： Compound 1 is new, and the other compounds were isolated from this plant for the first time. Compounds 5-7, 9, 11, 17, 18 and 20 exhibited inhibitory effects on the growth of human lung cancer cell A549 and compounds 5, 7, 12, 13, 17 and 19 showed anti-angiogenic effects in a zebrafish model.