中文摘要：

目的：观察小儿推拿在小儿哮喘不同时期对NO及H2S水平变化的影响。方法：按照随机原则将160例支气管哮喘患儿分为推拿组和哮喘组，急性发作期、慢性持续期各30例，缓解期各20例。哮喘组采用西药常规治疗，推拿组在西药常规治疗的基础上加用小儿推拿手法，测定治疗前和治疗后14天呼出气NO、血清NO及H2S水平。结果：支气管哮喘患儿血清NO及呼出气NO水平急性期高于慢性持续期，慢性持续期高于缓解期；急性期治疗后推拿组和哮喘组血清NO及呼出气NO水平均有下降，差异无统计意义（P〉0．05）；慢性持续期及缓解期治疗后推拿组血清NO及呼出气NO水平有显著下降，且推拿组下降幅度大于哮喘组，差异有统计学意义（P〈0．05）。血H2S水平急性发作期组显著低于慢性持续期组，慢性持续期组低于缓解期组，差异均有统计学意义（P〈0．01）。结论：NO水平及H2S水平与儿童支气管哮喘的炎症程度密切相关，小儿推拿能有效缓解小儿哮喘症状及降低血清NO及呼出气NO水平，提升血清H2S水平。

英文摘要：

Objective： To observe the effect of pediatric massage on the levels of NO and H2S in different periods of pediatric asth-ma. Methods： One hundred and sixty children with asthma were divided into massage group and asthma group according to the principle of random, and then the children in each group were divided into acute onset period subgroup （30 children）, chronic persistent period sub group （30 children）, and remission period subgroup （30 children） ; the children in asthma group were treated with western conventional therapy, while the children in massage group were treated with pediatric massage technique based on western conventional therapy; the levels of exhaled NO, serum NO, and serum H2S before treatment and at 14 days after treatment were measured. Results： In asthma group, the levels of serum NO and exhaled NO in acute onset period subgroup were higher than those in chronic persistent period subgroup, and the lev els of serum NO and exhaled NO in chronic persistent period subgroup were higher than those in remission period subgroup; after treatment, the levels of serum NO and exhaled NO in acute onset period subgroups of massage group and asthma group decreased significantly, but there was no statistically significant difference between the two groups （P 〉 0. 05） ; after treatment, the levels of serum NO and exhaled NO in chronic persistent period subgroups and remission period subgroups of massage group and asthma group decreased significantly, and the de-creasing amplitudes in massage group were statistically significantly higher than those in asthma group （ P 〈 0. 05 ） ; the level of serum H2S in acute onset period subgroup was lower than that in chronic persistent period subgroup, and the level of serum H2S in chronic persistent period subgroup was lower than that in remission period subgroup （P 〈 0. 01 ） . Conclusion ： The levels of NO and H2S are closely related to the degree of inflammation of bronchial asthma in children. Pediatric massage can effectively r