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小儿推拿对小儿哮喘不同时期IL-17、IL-33、IL-6水平变化的影响
  • ISSN号:1001-4411
  • 期刊名称:《中国妇幼保健》
  • 时间:0
  • 分类:R725.6[医药卫生—儿科;医药卫生—临床医学]
  • 作者机构:[1]河北联合大学中医学院,河北唐山063000
  • 相关基金:国际科技合作计划项目[2013DFG31080]国家自然基金项目(81303046]
中文摘要:

目的:观察小儿推拿对小儿哮喘不同时期IL-17、IL-33、IL-6水平变化影响。方法:将急性发作期、慢性持续期和缓解期哮喘婴儿100例,严格遵循随机分组的原则分为推拿组50例和哮喘组50例。哮喘组应用不同时期、不同基础治疗方式。推拿组在基础治疗的基础上,应用小儿推拿,两组各观察14天,在治疗前后取外周血,检测IL-17、IL-33、IL-6水平。结果:两组患儿检测急性发作期、慢性持续期,推拿组缓解期血清中IL-17、IL-33、IL-6水平,治疗后较治疗前明显下降(P〈0.05);急性发作期血清中IL一17水平,慢性持续期和缓解期治疗后推拿组血清中IL-17、IL-33、IL-6水平,与哮喘组比较有统计学差异(P〈0.05)。结论:小儿推拿手法可以通过降低血清中IL-17、IL-33、IL-6水平,来改善小儿哮喘的临床症状。

英文摘要:

Objective: To investigate the effect of massage on IL - 17,IL - 33 and IL - 6 of pediatric asthma in different time. Methods: 100 patientg in different time were enrolled and divided into two groups randomly. The asthma group (50 cases) were trea- ted with different foundation treatment in different periods, while massage group (50 cases) applied pediatric massage on the basis of foun- dation treatment, both groups were observed for 14 days. All patients were assessed with IL - 17, IL -33 and IL -6 in serum at the begin- ning of the training and 14 days after treatment. Results: Two groups were detected in different times, the levels of IL - 17, IL -33 and IL - 6 in massage group were lower in remission stage after treatment than before treatment ( P 〈 0. 05 ) ; compared with asthma group, the level of IL - 17 in acute stage, the levels of IL - 17, IL - 33 and IL - 6 in chronic duration and remission stage, were significant different in massage group. Conclusion : Massage maybe improve the clinical symptoms of pediatric asthma by descending the levels of IL - 17, IL - 33 and IL- 6 in serum.

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期刊信息
  • 《中国妇幼保健》
  • 北大核心期刊(2011版)
  • 主管单位:国家卫生和计划生育委员会
  • 主办单位:中华预防医学会 吉林省医学会
  • 主编:胡国义
  • 地址:长春市建政路971号
  • 邮编:130061
  • 邮箱:zgfybj@sina.com
  • 电话:0431-88929639 88923066
  • 国际标准刊号:ISSN:1001-4411
  • 国内统一刊号:ISSN:22-1127/R
  • 邮发代号:12-94
  • 获奖情况:
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版)
  • 被引量:101800