中文摘要：

利用微波促进的方法，以2,6-二氯苯甲醛、胺和巯基乙酸为原料，合成了系列N-3位不同取代基团的噻唑烷酮衍生物．部分化合物在Lawesson试剂作用下，合成了其系列噻唑烷4-硫酮衍生物．所有化合物通过IR，^1H NMR，MS和元素分析等方法确定结构．测试了化合物对黄瓜白粉病菌的抑制活性和对宫颈癌细胞的毒性作用，部分化合物表现出较好的生物活性．

英文摘要：

A series of thiazolidin-4-ones with different group on the position N-3 were synthesized by a three-component cyclocondensation of 2,6-dichlorobenzaldehyde, amines and 2-mercaptoacetic acid using a microwave-assisted method. Some corresponding tbiazolidin-4-thione derivatives were also prepared in the presence of Lawesson＇s reagent. The structures of the synthesized compounds were confirmed by IR, ^1H NMR, MS and elemental analysis. Antifungal （Sphaerotheca fusca Blum.） and cytotoxic activities against Hela cell of the compounds were evaluated, and some compounds showed good biological activities.