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中文摘要：
采用液相色谱－质谱－质谱联用法测定了１８名健康男性受试者口服苯磺酸氨氯地平片和络活喜后不同时刻血浆中氨氯地平的浓度，并求出主要药物动力学参数，受试者口服含氨氯地平１０ｍｇ的受试制剂和参比制剂后，血浆中氨氯地平的Ｔｍａｘ分别为（５．６±１．８）ｈ和（４．７±１．２）ｈ，Ｃｍａｘ分别为（７．３６±２．０４）ｎｇ／ｍＬ和（６．７２±１．４１）ｎｇ／ｍＬ，ｔ１／２分别为（３８．７±１４．２）ｈ和（４．７±
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