中文摘要：

在生活方式，临床的考试，在 CDH1 基因的多型性和繁体中文药(TCM ) 之中探索协会的目的胃的癌症(GC ) 的症候群区别。387 个 GC 病人的一张基于医院的人口在江苏省被调查的方法。关于生活方式和临床的检查的相关信息被一张标准问询表收集。在 CDH1 的四已知的单个核苷酸多型性(SNP ) 被聚合酶链反应结扎察觉反应方法调查。统计分析被社会科学统计套装软体 16.0 软件进行。结果显示出的结果那饭持续时间和 glutamic 焦葡萄酸 transaminase 的地位显著地与 GC 的 TCM 症候群区别被联系(两 P < 0.05 ) 。任何一个都没在 GC 的九种症候群类型之中在他们的分布在 E-cadherin (CDH1 ) 基因的四 SNP 完成重要差别(两 P > 0.05 ) 。然而，重要差别在在 GC 的几种症候群类型之间的 rs13689 遗传型分布被观察，建议 rs13689 与 GC 的症候群区别被相关。生活方式，临床的考试和 CDH1 基因多型性的结论综合分析能贡献 GC 症候群类型的更好的理解并且可以由成层改进干预的功效疾病根据 TCM 标准。

英文摘要：

OBJECTIVE： To explore the association among lifestyle, clinical examination, polymorphisms in CDH1 gene and Traditional Chinese Medicine（TCM） syndrome differentiation of gastric cancer（GC）. METHODS： A hospital-based population of 387 GC patients was investigated in Jiangsu province. Relevant information regarding lifestyle and clinical examination were collected by a standard questionnaire. Four known single nucleotide polymorphisms（SNPs） in CDH1 were investigated by polymerase chain reaction-ligation detection reaction methods. Statistical analysis was conducted by SPSS 16.0 software. RESULTS： The results showed that meal duration and the status of glutamic pyruvic transaminase were significantly associated with TCM syndrome differentiation of GC（both P0.05）. None of the four SNPs in the E-cadherin（CDH1） gene achieved significant differences in their distributions among the nine syndrome types of GC（both P0.05）. However, significant differences were observed in rs13689 genotype distributions between several pairs of syndrome types of GC, suggesting that rs13689 is correlated with the syndrome differentiation of GC. CONCLUSION： Integrated analysis of lifestyle, clinical examination and CDH1 gene polymorphisms can contribute to a better understanding of the GC syndrome types and may improve the efficacy of interventions by stratifying disease according to TCM criteria.