目的 探讨碘对甲状腺结节性疾病的影响.方法 采用“尿碘定量检测法”对患有甲状腺结节(术前组)、已行甲状腺手术(已手术组)和正常人群(正常对照组)的尿碘水平进行检测.结果 三组尿碘水平构成比不同(P<0.001);疾病组尿碘中位数为碘过量(323.05μ g/L),已手术组尿碘中位数为碘充足(177.11μg/L),正常对照组尿碘中位数为碘超足量为(261.84μg/L),疾病组尿碘中位数与已手术组尿碘中位数及正常对照组尿碘中位数比较差异均有显著性(P<0.05);已手术组尿碘中位数与正常对照组尿碘中位数比较无显著性差异(P>0.05).结论 甲状腺结节性疾病患者碘过量,既往患甲状腺结节性疾病已行手术切除的患者碘充足,正常人群碘超足量;甲状腺结节性疾病的发病可能与碘摄入过量有关;甲状腺结节性疾病患者行手术治疗可能可以使体内碘水平下降.
[Objective] To explore the impact of iodine on thyroid nodular disease. [Methods] The value of urine iodine was measured in thyroid nodular diseases patients (disease group), nodular thyroid postoperative patients (postoperative group) and normal people (control group) by the urine iodine quantitative detection method. [ Results ] Comparing the constituent ratio of urine iodine levels, three groups have different constituent ratio of urine iodine levels (P 〈0.001). The median of urine iodine (MUI) in disease group was excessive iodine (323.05 μg/L), the postoperative group was adequate iodine (177.111xg/L), the control group was more than adequate iodine(261.84 μg/L). The median of urine iodine in disease group was higher than the control group and postoperative group, the difference had statistical significance. [ Conclusions] The patients with thyroid nodular diseases suffer excessive iodine, the patients with nodular thyroid postoperative suffer adequate iodine, health People suffer more than adequate iodine. The incidence of thyroid nodular disease may be related to excessive iodine intake. The patients with thyroid nodular disease underwent surgical treatment may be able to make the iodine levels down.