中文摘要：

目的通过对子宫肌瘤患者的健康相关生活质量问卷的分析,了解子宫肌瘤患者的症状严重程度与生活质量的关系及生活质量各领域之间的相关性。方法回顾性分析重庆医科大学附属第一医院HIFU中心2013年行超声消融的共302例患有子宫肌瘤的女性患者的子宫肌瘤症状及健康相关生活质量问卷（UFS-QOL）量表及SF-36量表。结果 UFS-QOL量表中症状严重程度领域（SSS）的Cronbach′sα系数为0.794,健康相关生活质量亚量表（HRQL）的Cronbach′sα系数为0.953,说明量表的内部一致性较好。症状组子宫肌瘤患者的SSS得分明显高于无症状组（P〈0.05）,除性功能领域外,该组子宫肌瘤患者的HRQL评分明显低于无症状组子宫肌瘤患者（P〈0.05）。无症状组子宫肌瘤患者的SSS与HRQL各领域的相关程度一般,而UFS-QOL中的活动受限、精力/心情和生活失控三领域之间呈线性正相关（P〈0.05）,症状组子宫肌瘤患者其UFS-QOL量表中SSS与对疾病的顾虑、活动受限及精力/心情3个领域间呈线性负相关（P〈0.05）,其中活动受限与对疾病的顾虑、精力/心情领域呈线性正相关（r=0.776、0.741,P〈0.05）。结论子宫肌瘤的相关症状对子宫肌瘤患者的生活质量有影响,且患者对生活质量各领域间的评价也相互影响。

英文摘要：

Objective To know the relationship between the uterine fibroid symptom severity and the quality of life and the correlation among all the subscales of the quality of life base through analysis of the questionnaires of the uterine fibroids health-related quality of life.Methods Retrospectively analyze the UFS-QOL subscales and SF-36 subscales of the 302 women with uterine fibroids who underwent ultrasound ablation in the high intensity focused ultrasound center of the First Affiliated Hospital of Chongqing Medical University in 2013.Results The Cronbach′sαof the UFS-QOL symptom severity subscale and the HRQL subscales were 0.794 and 0.953,reflecting adequate internal consistency.Except the sexual function field,the symptomatic group reported significantly greater symptom severity and worse health-related quality of life（HRQL）than the asymptomatic group（P〈0.05）.Spearman′s correlations between the symptom severity subscale and each HRQL subscales were moderately in the asymptomatic group,there was a linear positive correlation between the UFS-QOL subscales of activities,energy/mood and control（P〈0.05）.In the symptomatic group,there was a linear negative correlation between the symptom severity subscale and the UFS-QOL subscales of concern,activities,energy/mood（P〈0.05）,and there was a linear positive correlation between the UFS-QOL subscale of activities and the UFS-QOL subscales of concern,energy/mood.Conclusion Uterine fibroids related symptoms have an impact on the quality of life in women with uterine fibroids,and the assessments among the subscales of the quality of life influence each other.