中文摘要：

优化 chitosan microspheres 的准备过程并且学习它的装载能力， chitosan microsphere 被 crosslinking 与 glutaraldehyde，和牛的浆液白朊(BSA ) 准备被吸收到 chitosan microsphere 上。扫描电子显微镜(SEM ) ， Fourier 变换红外线的光谱学(FITR ) ， TA 仪器和希腊语的第六个字母电位计分析器被用来关于 microspheres 的尺寸，热人物，形态学，和希腊语的第六个字母潜力描绘参数。装载能力并且在 vitro，版本测试被执行。结果证明有粒子的 chitosan microsphere 缩放不到 10 m 并且断然收费了( +25.97and 好分散， CMS@CS 是自我装配的进一部稠密的电影，这部电影与在固定温度增加暂停集中变厚，吗并且更多的订的电影在暂停集中的 1 wt%被获得并且 50 ?府寬謹

英文摘要：

To optimize the preparation process of chitosan microspheres and study its loading capacity, chitosan microsphere was prepared by crosslinking with glutaraldehyde, and bovine serum albumin （BSA） was absorbed onto chitosan microsphere. Scanning electron microscope （SEM）, Fourier transform infrared spectroscopy （FITR）, TA instruments and zeta potentiometer analyzer were used to characterize the parameters with respect to size, thermal characters, morphology, and zeta potential of the microspheres. The loading capability and in vitro release tests were carried out. The results showed that chitosan microsphere with particle size less than 10 μm and positively charged （＋25.97±0.56 mV） can be obtained under the aldehyde group to amino group ratio at 1：1. A loading capacity of BSA at 28.63±0.15 g/100 g with corresponding loading efficiency at 72.01±1.44% was obtained for chitosan microsphere. In vitro test revealed a burst release followed by sustained-release profile.