中文摘要：

目的研究LASIK手术对角膜前、后表面Q值的变化以及与近视等效球镜相关性。方法 2009年6月-9月行准分子激光近视矫治手术病人96例192眼,按近视屈光度分为低度近视组（-3.00D--6.00D）和高度近视组（〉-6.00D）,分别在术前和术后1周行Pentacam眼前节分析系统检查,测量角膜前后表面Q20、Q25、Q30、Q35值并进行统计学分析。结果手术前中度和高度近视角膜前后表面Q20、Q25、Q30、Q35差别无统计学意义（P〉0.05）。手术后角膜前后表面的Q20、Q25、Q30、Q35值均向正值方向改变,且前表面的变化明显,等效屈光度数越大,术后Q值向正值变化越大。中度近视和高度近视等效屈光度与角膜前表面ΔQ20（r=0.29,P=0.004）、ΔQ25（r=0.30,P=0.003）、ΔQ30（r=0.31,P=0.002）显著相关,与ΔQ35相关（r=0.23,P=0.021）;与角膜后表面ΔQ值无相关（r分别-0.115,-0.12,-0.135,-0.152,P〉0.05）。结论 LASIK手术后角膜前后表面Q20、Q25、Q30、Q35值均有变化。并且角膜前表面Q值与等效屈光度相关。

英文摘要：

Objective To study the effect of laser in situ keratomileusis（LASIK） on Q values of anterior and posterior corneal surface and its relation with myopia.Methods Ninety-six patients（192 eyes） undergone LASIK in June-September 2009 were divided into low myopia group and high myopia group according to their diopter.Pentacam was performed to detect the Q20,Q25,Q30 and Q35 values of the anterior and posterior corneal surface before and 1 week after LASIK.Results No difference was observed in Q20,Q25,Q30 and Q35 values of the anterior and posterior corneal surface between low and high myopia groups before operation.The Q20,Q25,Q30 and Q35 values of the anterior and posterior corneal surface were significantly changed after operation.The diopter was related with ΔQ20（r=0.29,P=0.004）,ΔQ25（r=0.30,P=0.003）,ΔQ30（r=0.31,P=0.002） and ΔQ35（r=0.23,P=0.021） of anterior corneal surface but not with ΔQ of the posterior corneal surface（r=-0.115,-0.12,-0.135,-0.152,P0.05） in low and high myopia groups.Conclusion The Q20,Q25,Q30 and Q35 values of the anterior and posterior corneal surface will change after LASIK.The Q values of anterior corneal surface are related with equivalent diopter.