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孕妇TORCH感染情况与不良妊娠结局的相关性

ISSN号：1001-4411
期刊名称：《中国妇幼保健》
时间：0
分类：R181.3[医药卫生—流行病学;医药卫生—公共卫生与预防医学]
作者机构：[1]广西壮族自治区妇幼保健院检验科,广西南宁530003
相关基金：广西壮族自治区卫生重点科研课题[重2012020]

作者：李东明[1], 张硕[1], 陶春凤[1], 黄海锋[1], 周晖登[1], 佘尚扬[1]

关键词： TORCH感染, 孕妇, 不良妊娠结局, TORCH, Pregnant woman, Adverse pregnancy outcome

中文摘要：

目的探讨南宁地区孕妇TORCH感染状况及其与不良妊娠结局的关系。方法选取2006年1月～2014年6月在该院进行孕期检查的孕妇50590例为研究对象，采用ELISA法检测孕妇血清TORCH—IgM阳性情况。依据临床不良妊娠情况进行分组，分析各组孕妇TORCH—IgM阳性率的差异。结果孕妇TORCH—IgM阳性率为3．57％，其中CMV—IgM阳性率（1．25％）高于TOX—IgM（0．45％）、RV—IgM（0．57％）、HSVⅡ－IgM（0．61％）和HSVI—IgM（0．68％），不良妊娠史组阳性率（5．67％）高于正常组（3．24％），差异有统计学意义（P〈0．05）。孕妇脐血TORCH—IgM阳性率为0。73％，其中CMV—IgM阳性率（0．70％）高于TOX—IgM（0．02％）和RV—IgM（0．04％），不良妊娠组阳性率（2．70％）高于正常组（0．22％），差异有统计学意义（P〈0．05）。结论TORCH感染在孕妇和胎儿中均有发生，且与不良妊娠结局有关，应加强TORCH的筛查、预防和治疗。

英文摘要：

Objective To explore the relationship between TORCH infection in pregnant women and adverse pregnancy outcome in Nanning region. Methods A total of 50 590 pregnant women receiving pregnant examination in this hospital from January 2006 to June 2014 were selected as research group, ELISA was used to detect the positive rate of serum TORCH-IgM. The pregnant women were divided into different groups according to adverse clinical pregnancy history, the difference of positive rate of serum TORCH-IgM in different groups was analyzed. Results The positive rate of TORCH-IgM was 3.57% , the positive rate of CMV-IgM （ 1.25% ） was higher than those of TOX- IgM （0. 45% ） , RV-IgM （0. 57% ）, HSV II -IgM （0. 61% ）, and HSV I -IgM （0. 68% ） ; the positive rate of TORCH-IgM in adverse pregnancy history group was 5.67% , which was statistically significantly higher than that in normal group （3.24%）（P〈0. 05 ） . The positive rate of TORCH-IgM in umbilical cord blood was 0. 73% , the positive rate of CMV-IgM was 0. 70% , which was higher than those of TOX-IgM （0.02%） and RV-IgM （0. 04% ） , the positive rate of TORCH-IgM in adverse pregnancy history group was 2. 70% , which was statistically significantly higher than that in normal group （ 0. 22% ）（ P〈0. 05 ） . Conclusion TORCH infection can occurs in pregnant women and fetuses, and it is associated with adverse pregnancy outcome. It is necessary to pay attention to screening, prevention, and treatment of TORCH.

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