中文摘要：

目的：探讨聚乳酸-聚羟基乙酸共聚物（PLGA）对明胶的改性效果。方法：（1）将PLGA和明胶分别以9：1，8：2，7：3，6：4，5：5，3：7质量比制成膜状试件。（2）以扫描电镜观察试件的微结构。（3）以材料试验机测试其力学性质。（4）以PBS（pH 7.4）为人工降解液考察其在体外在8周内的降解情况。结果：（1）在上述范围内支架均质程度和机械性能随明胶含量增大而变差。（2）体外降解期间支架最大吸水率和失重速率随明胶含量增大而增大。结论：经PLGA改性后的明胶的上述各项指标均发生了显著变化，作为备选组织工程材料，复合体系中明胶含量不宜多于40%.

英文摘要：

Obstract：To evaluate the feasibility of PLGA-Gelatin complex as potential biomaterial of tissue engineering,samples fabricated with different mass ratio of PLGA and gelatin were detected by SEM.Mechanical test was performed,and their behaviors of degradation were observed.Results showed that this complex had a honeycomb like structure,suitable mechanical property and degrada- tion performance,thus make it to be a potential biomaterial of tissue engineering.