中文摘要：

目的：探讨经聚乳酸-聚羟基乙酸共聚物（PLGA）改性的水溶性胶原在体外对牛血清白蛋白（BSA）的缓释性能。方法：将PLGA、胶原和BSA制备成复合物，用ELISA法检测本复合物对BSA的缓释性质．结果：本复合物约以6.61ng／d的速率稳定地缓释BSA，在30天的考察期内，BSA累积释放率达到43％，本复合物形态保持完好：结论：本PLGA-胶原复合物有望发展成为一种体内植入型，具有对生物活性物质长效缓释性质的组织工程支架。

英文摘要：

Objective： To investigate the sustained-release property of the conduit for bovine serum albumin （BSA） with polylactic acid-co-glycolic acid （PLGA） copolymer. Methods： Sustained-release property of the conduit for bovine serum albumin （BSA） was detected by ELISA method in vitro. Results： Conduit could release BSA steadily with a rate of 6.6 ng/d （ r=0.994 ） or so. The accumulative release ratio was up to 43% in the one month period and the shape of conduit was still originally kept. Conclusion： The conduit constructed would be a potential implanting support with prolonged sustained release effect for tissue engineering.