中文摘要：

目的探讨磁共振灌注成像对肝硬化增生性结节和小肝癌的鉴别诊断价值。方法分析经临床和病理证实11例11个肝硬化增生性结节（DN）和18例18个小肝细胞癌（SHCC）的磁共振灌注成像资料，获取每个病灶的时间-信号强度曲线（TIC），记录病灶的峰值时间（TTP），计算肝脏动脉灌注指数（HPI）并进行比较。结果DN的TIC呈缓升缓降型；SHCC的TIC呈速升速降型。DN和SHCC的TTP分别为（39．56±1．67）S、（25．21±1．38）s，FIPI分别为0．26±0．04、0．75±0．02，DN和SHCCTTP、HPI有统计学差异（P〈0．05）。结论MR灌注成像技术可以提供比传统图像更多有用的肿瘤血供信息，有助于鉴别DN和SHCC．

英文摘要：

Objective To explore the value of MR perfusion weighted imaging in differential diagnosis of dysplastic nodules in cirrhosis （DN） and small hepatocellular carcinoma （SHCC）. Methods MR perfusion weighted imaging of 11 patients with 11 DN and 18 patients with 18 SHCC proved by clinic and pathology were reviewed. Time-intensity curve （TIC） of each mass was got. The time to peak （TTP） of each mass was recorded and hepatic perfusion indexes （HPI） were calculated and compared. Results The DN TIC was ascending and decreasing slowly; the SHCC TIC was ascending and decreasing rapidly. The DN and SHCC TIC was （39.56 ± 1.67） s, （25.21 ± 1.38） s, HPI was 0.26 ± 0.04, 0.75 ± 0.02, TTP and HPI had statistic significance between DN and SHCC groups （P 〈0.05）. Conclusions MR perfusion weighted imaging can effectively reveal blood supply information of DN and SHCC, and help for the differential diagnosis of DN and SHCC.