炔烃经水合反应生成酮是有机合成中最重要和最基本的进行官能团转换的方法之一,我们提供了一种价廉且具有高选择性的硫酸高铈催化炔烃水合方法.实验结果表明:在硫酸高铈(0.1mmol)、浓硫酸(0.06mL)、水(0.02mL)和苯(5mL)且反应温度为70℃的反应条件下,炔烃(1mmol)可以顺利发生水合反应生成酮.
An inexpensive and highly selective method for cerium(IV) sulfate-catalyzed hydration of alkynes was provided. Treatment of alkynes (1 mmol) with Ce(SO4)2 (0.1 mmol), H2SO4 (conc. 0.06 mL), water (0.02 mL) and benzene (5 mL) at 70 ℃ afforded the corresponding ketones in moderate to excellent yields.