目的:观察丹栀逍遥散联合氟西汀对中风后抑郁症的临床疗效。方法:将400例中风后抑郁症患者随机分为治疗组和对照组,每组各200例。对照组口服氟西汀,治疗组在对照组的基础上加服丹栀逍遥散,观察两组患者的临床疗效及治疗前后汉密尔顿抑郁量表(HAMD)评分情况。结果:治疗组有效率为92.0%,对照组有效率为71.0%,两组患者临床疗效比较,差异有统计学意义(P〈0.05)。两组患者治疗后HAMD评分均较治疗前明显下降,且治疗组低于对照组,差异有统计学意义(P〈0.05)。结论:丹栀逍遥散联合氟西汀治疗中风后抑郁症疗效较好。
Objective To observe the clinical therapeutic effect of modified Danzhi Xiaoyao Powder combined with fluoxetine in treating 200 cases with post stroke depression. Methods : A total of 400 Post-stroke Depression (PSD) patients were randomized into the treatment group and control group, with 200 eases in each group. The control group were treated with fluoxetine,in the treatment group and control group based on the given modified l)anzhi Xiaoyao Powder,observed before and after treatment in two groups of patients with Hamilton Depression Scale (HAMD) score. Resuhs:The effective rate of the treatment group was 92%, and the control group was 71%. The difference was statistically significant (P 〈 0.05 ). After treatment,the HAMD scores of the two groups were significantly decreased compared with before treatment, and the treatment group was lower than the control group, the difference was statistically significant (P 〈 0.05 ). Conclusion : Modified Danzhi Xiaoyao Powder Combined with fluoxetine in treatment of depression after stroke curative effect is better.