目的观察中药芪夏消瘿汤治疗甲状腺功能亢进症的临床疗效。方法选择甲状腺功能亢进症患者70例,随机分为两组,治疗组予以芪夏消瘿汤和小剂量他巴唑,对照组用大剂量他巴唑。治疗前后观察两组临床疗效,并检测两组L、T4、TSH、飓、啊及T细胞亚群、血常规、肝肾功能。结果治疗组总有效率为91.43%,明显高于对照组之74.29%(P〈0.05);治疗后两组L、T4、FT3、FT4水平下降,鸭H增高,与治疗前相比差异有统计学意义(P〈0.05),组间比较差异无统计学意义(P〉0.05);治疗组治疗后免疫指标明显改善(P〈0.05),对照组无明显改善(P〉0.05)。结论芪夏消瘿汤能有效治疗甲状腺功能亢进症,减少西药用量.并能调节机体免疫功能.升高白细胞。
Objective: To observe the clinical effect of Qixiaxiaoying Decoction treating hyperthyroidism. Meth- ods: 70 patients with hyperthyroidism were randomly divided into 2 groups. Treatment group was given the Qixi- axiaoying Decoction and small doses of methimazole. Control group was given large doses of methimazole. Before and after treatment,some indicators were detected and compared between the 2 groups such as FT3,FT4,TSH,T cells and the clincial efficacy. Results: After treatment,the total effective rate of treatment group was 91.43% which was significantly higher than 74.29% of control group (P〈 0.05). Compared with the index before treatment, these indicators were reduced Obviously such as T3,T4, FT3 and FT4. Meanwhile, TSH was increased remarkably (P 〈 0.05 ). There were no statistical differences about these indicators in control group(P〉 0.05 ). Conclusion: Qixi- axiaoying Decoction can effectively regulate thyroid hornone levels of hyperthyroidism and enhance the function of T cells.