目的观察芪夏消瘿汤和生白升血胶囊加减治疗甲状腺功能亢进症(简称甲亢)伴白细胞减少的临床疗效。方法选择甲亢合并白细胞减少66例,随机分成两组,治疗组40例,对照组26例。治疗组每日服用生白升血胶囊和芪夏消瘿汤加减中药水煎剂1付,连续服用14d。对照组每日服用地榆生白片,3片/次,3次/日,连续服用14d。服药前后进行有关项目对比。结果治疗组患者治疗后临床症状改善、白细胞总数上升38例,有效率95.0%,游离三碘甲状腺原氨酸为(9.60±1.08)pmol/L,游离四碘甲状腺原氨酸(37.40±1.70)pmol/L,甲状腺刺激激素为(0.11±1.11)uIU/mL。对照组白细胞总数上升21例,有效率80.8%,但甲状腺激素无变化,两组相比差异有统计学意义(P【0.05)。结论芪夏消瘿汤和生白升血胶囊加减能升高白细胞,改善甲状腺激素水平。
Objective To observe the clinical effect of Qi Xia Xiao Ying Tang and Sheng Bai Sheng Xue cap-sule in treating hyperthyroidism with leukopenia .Methods A total of 40 hyperthyroidism patients with Leukopenia , enrolled as treatment group were given Qi Xia Xiao Ying Tang and Sheng Bai Sheng Xue Capsule .A total of 26 hy-perthyroidism patients with Leukopenia ,enrolled as control group ,were given Di Yu Sheng Bai tablets .Relative inde-xes were compared before and after treatment between the two groups .Results After treatment ,serum levels of free triiodothyronine ,free thyroxin decreased ,thyrotropic-stimulating hormone level increased ,and the differences with re-sults detected before treatment were significant (P<0 .05) ,and level of white blood cells was also increased and with significant difference (P<0 .05) .Conclusion Qi Xia Xiao Ying Tang and Sheng Bai Sheng Xue Capsule could effec-tively regulate serum levels of thyroid hormones in patents with hyperthyroidism and increasing the number of WBC .