中文摘要：

针对科学活动中心中定性与定量研究的困境,定性与定量综合集成法的研究阐明了科学活动主体中心期的转移及转移过程中的多中心性现象。科学活动主体中心期的转移及转移过程中的多中心性现象有其历史地理基础：通过历史地理化过程,科学影响因素的地域集聚产生科学活动的整体效应,同时伴随着科学社会化过程,形成科学中心;地理历史化过程加强了科学活动的整体效应和社会科学化过程,进一步整合了科学资源,使已经存在的小的科学活动中心形成大的科学活动主体中心,使世界科学活动中心发生转移。

英文摘要：

There are two main stream ways for researching the problem of scientific activities center： qualitative and quantitative methods.But not only their aim,consequence,but also relationship between them are inconsistent.Contraposing these researching dilemma,this paper re-explained the phenomenon of scientific activities center with the method of Metasynthesi.Based on the method of Metasynthesi,for the phenomenon of scientific activities center,on the substance,it＇s both multicentred and independence.Both phenomenon have the foundation of historical and geographical,which including the progress of history geographical and geography historical.By means of history geographical,these factors influenced science development gather in some areas and produced ＇bulk effect＇,promoted science socialization,and formed scientific activities center.And at the same time,geography historical strengthened the ＂bulk effect＂,promoted society scientific,integrated scientific resources further,making some small scientific activities centers became big centers,and then the main scientific activities centers changed.