目的探讨LFK-SLT30半导体激光联合聚多卡醇泡沫硬化剂治疗下肢浅静脉曲张的临床效果和安全性。方法回顾性分析天津市第一中心医院2013年4月至2015年4月行传统手术的105例患者(单纯手术组)和行腔内激光联合聚多卡醇治疗的113例患者(联合治疗组)的临床资料。结果联合治疗组和单纯手术组的手术时间[(50±12)min比(70±10)min],术中出血量[(19±6)ml比(41±8)ml]比较,差异有统计学意义(P〈0.05)。单纯手术组并发症发生率高于联合治疗组[15.2%(16/105)比6.3%(7/113)],差异有统计学意义(χ^2=4.717,P=0.030)。218例患者中,1年随访率85.3%(186/218),2年随访率76.6%(167/218),3年随访率60.6%(132/218),平均随访(20±13)个月,2组复发率[0比3.5%(4/113)]差异无统计学意义(χ^2=3.786,P=0.123)。结论腔内激光联合泡沫硬化剂治疗下肢浅静脉曲张创伤小、安全、有效,并发症少。
Objective To explore the clinical efficacy and safety of LFK-SLT30 semiconductor laser combined with polidocanol for the treatment of varicose veins of the lower extremities. Methods The clinical data of 105 patients treated by traditional surgery (surgery group) and 113 patients with endovascular laser treatment (EVLT) combined with polidocanol ( combination group) were retrospectively analyzed from Apr 2013 to Apt 2015. Results The operative time [ (50 ± 12) rain vs. (70 ± 10) mini and blood loss [ (19 ± 6)ml vs. (41 ± 8)ml ] between combination group and surgery group were significantly different ( P 〈 0. 05 ). The rate of complications in surgery group was significantly higher than that in the combination group[ 15.2% (16/105)vs. 6. 3% (7/113) , χ^2 =4. 717, P =0. 030]. The overall 1 ', 2' and 3 year follow-up rate was 85.3% ( 186/218), 76. 6% ( 167/218), and 60. 6% (132/218). The average follow up was (20 ± 13 )months. No significant difference existed in the rate of recurrence I 0 vs. 3.5% (4/113) , χ^2= 3. 786, P = 0. 123 ] between the two groups. Conclusions EVLT combined with foam sclerotherapy is as effective as surgery, while resulting in less complications, less invasive, safer and more effective for the treatment of varicose veins of the lower extremities.