欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
核酸适体是一类体外筛选且可与目标分子高效、高特异亲合的RNA或DNA寡核苷酸片段,与常规识别分子（如抗体等）相比,核酸适体作为一类新型识别分子具有明显特色和优势,已被广泛应用于生物传感等分子识别和应用研究领域。本文就基于核酸适体的电化学生物传感器（标记型和非标记型）的近期进展作简要评述,包括适体简介、标记型（＂信号衰减＂型、＂信号增强＂型、酶标记型和纳米粒子标记型）和非标记型电化学适体生物传感器等内容。
英文摘要：
The aptamers are DNA or RNA oligonucleotides selected in vitro that can bind their targets with high affinity and high specificity. As a kind of new and special recognition molecules, the aptamers present notable advantages over conventional recognition molecules, such as antibody, thus they have received great attention and been widely utilized in various fields involving molecular recognition and relevant applications, especially in biosensing. In this review, we briefly summarize the recent progress of aptamer-based electrochemical biosensors, involving introduction of aptamer and ＂signal-on＂ type, ＂signal-off＂ type, enzyme-labeled, nanoparticle-labeled and nonlabeled aptamer-based electrochemical biosensors.
同期刊论文项目
同项目期刊论文
Polymeric bionanocomposite cast thin films with in situ laccase-catalyzed polymerization of dopamine
High-performance amperometric sensors using catalytic platinum nanoparticles-thionine-multiwalled ca
Detection of adherent cells using electrochemical impedance spectroscopy based on molecular recognit
Magnetically enhanced cytotoxicity of paramagnetic selenium-ferroferric oxide nanocomposites on huma
Immobilization of enzymes at high load/activity by aqueous electrodeposition of enzyme-tethered chit
Novel polymeric bionanocomposites with catalytic Pt nanoparticles label immobilized for high perform
Square wave voltammetric determination of Hg(II) using thiol functionalized chitosan-multiwalled car
Extraction and preconcentration of (-blockers in human urine for analysis with high performance liqu
A study on separation and extraction of four main alkaloids in Macleaya cordata (Wild) R. Br. with s
Biofuel cell and phenolic biosensor based on acid-resistant laccase-glutaraldehyde functionalized ch
Electropolymerization of preoxidized catecholamines on Prussian blue matrix to immobilize glucose ox
Electropolymerization of catecholamines after laccase-catalyzed preoxidation to efficiently immobili
Chemical/biochemical preparation of new polymeric bionanocomposites with enzyme labels immobilized a
An EQCM study on the interaction of heparin with the charge-transfer complex generated during o-toli
A third-generation hydrogen peroxide biosensor based on horseradish peroxidase immobilized in a tetr
Preparation of Pt/multiwalled carbon nanotubes modified Au electrodes via Pt-Cu co-electrodeposition
Synthesis and characterization of novel quinone-amine polymer/carbon nanotubes composite for sensiti
Preparation of chitosan-dopamine- multiwalled carbon nanotubes nanocomposite for electrocatalytic ox
Electrochemical quartz crystal impedance and fluorescence quenching studies on the binding of carbon
Construction as well as EQCM and SECM characterizations of a novel nafion/glucose oxidase-glutaralde
Electrochemical quartz crystal microbalance studies on the codeposition of dextran sodium sulphatewi
Quartz crystal microbalance and electrochemical cytosensing on a chitosan/multiwalled carbon nanotub
One-pot preparation of polymer–enzyme–metallic nanoparticle composite films for high-performance bio
Biofuel cell and phenolic biosensor based on acid-resistant laccase–glutaraldehyde functionalized ch
Highly sensitive and surface-renewable electrochemical quartz crystal microbalance assays of heparin
Electrochemical quartz crystal microbalance studies on enzymatic specific activity and direct electr
Highly Sensitive glucose biosensor based on one-pot biochemical preoxidation and electropolymerizati
Electrodeposition of biocompatible hydroxyapatite matrix to immobilize glucose oxidase for sensitive
Electrochemical quartz crystal microbalance study of covalent tethering of carboxylated thiol to pol
Electrosynthesized poly(1,6-hexanedithiol) as a new immobilization matrix for Au-nanoparticles-enhan
Simultaneous quartz crystal microbalance-electrochemical impedance spectroscopy study on the adsorpt
位置：