目的:了解网络成瘾者的失匹配负波(MMN)的波形特点和变异情况。方法:应用Odd—ball模式在非注意状态下对网络成瘾组和对照组进行事件相关电位MMN成分的检测,分析其波形特点及潜伏期、波幅的变化情况。结果:网络成瘾组与对照组均出现典型的MMN波形,其中以Fz导联波幅最大;网络成瘾组在Fz导联的MMN的波幅明显高于对照组[网络成瘾组为(9.58±3.27)12V,对照组为(7.52±3.36)pV,P〈0.053,但两组潜伏期比较,差异无显著意义[网络成瘾组为(212.00±22.53)ms,对照组为(217.55±25.81)ms,P〉0.05]。结论:网络成瘾组MMN的波幅升高,可能与其对信息变化的自动检测功能出现一定程度的下降有关。
Objective: To investigate the characteristics and variation of mismatch negativity (MMN) in patients with internet addiction. Methods: MMN examinations were performed in the internet addiction group and the normal control group in the non-attention state, and then the characteristics of waveforms and the variations of MMN latency and amplitude were analyzed. Results.. Typical MMN waveforms were recorded both the internet addiction group and the control group, of which the largest amplitude was at Fz lead. The amplitude of MMN at Fz lead in the internet addiction group was signifi- cantly higher than in the control group[the former(9.38±3.27)μV,the latter group(7.52 ± 3.36)μV, P〈0. 052, while the latency of MMN was no significant difference between the two groups[The internet addiction group(212.00±22.53)ms,the control group(217.55±25.81)ms,P)0.05]. Conclusion: Obvious increase of MMN amplitude in patients with internet addiction may be related with the reduetion of their auto-detection function of information changes to some extent.