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逍遥散对肝郁脾虚证模型大鼠海马CA1区和杏仁核BLA区GluR2阳性细胞数变化的影响
  • 期刊名称：中华中医药杂志
  • 时间：0
  • 页码：1198-1201
  • 分类：R255.2[医药卫生—中医内科学;医药卫生—中医学]
  • 作者机构：[1]北京中医药大学,北京100029, [2]中国中医科学院,北京100700, [3]北京市崇文区永外社区卫生服务中心,北京100075, [4]北京市普仁医院,北京100062, [5]暨南大学医学院,广州510630
  • 相关基金：国家高技术研究发展计划（863计划）（No.2008AA02Z406）; 国家杰出青年科学家基金资助项目（No.30825046）。
  • 相关项目：中医诊断学
作者： 岳利峰|陈家旭|霍素坤|梁媛|李晶晶|岳广欣|奚胜艳|
关键词： 亚健康, 证候, 问卷, 信度, 效度, Sub-health, Syndrome, Questionnaire, Reliability, Validity
中文摘要：

目的：评价＂亚健康状态中医证候调查问卷＂的信度和效度。方法：3个中心采集亚健康人群有效样本268例,健康人群有效样本86例,并对其中65例亚健康人群实施了再调查,63例亚健康人群进行了效度检测。结果：①信度检测方面,问卷总体及各维度的克朗巴赫α系数值、折半系数值和稳定系数值分别在0.70-0.95,0.67-0.87,0.88-0.98之间;②效度检测方面,校标效度表现不佳;区分效度表现为亚健康人群、健康人群在问卷各维度及总体得分均具有明显的统计学意义（P〈0.01）;结构效度采用因子分析,按特征根值〉1提取出12个公因子,累积贡献率为63.632%。结论：该问卷具有较好的信度和效度,可以作为亚健康状态中医证候分类的一个工具和尺度。

英文摘要：

Objective： To evaluate the reliability and validity of TCM syndrome questionnaire of sub-health state.Methods： Through the investigation,we collected 268 valid cases of sub-health population and 86 valid cases of health population from 3 centers,and we retested 65 cases of sub-health population,tested the validity of 63 cases of sub-health population.Results： ① On the reliability,in terms of the the overall and the dimensions of the questionnaire,the Cronbach α coefficient,split-half coefficient and stability coefficient range from 0.70 to 0.95,0.67 to 0.87,0.88 to 0.98 respectively;② On the validity,in addition to poor criterion validity,there are clear statistical significance（P0.01）in the dimensions and overall scores between the people of sub-health and healthy in the questionnaire;through factor analysis,there are 12 factors that the eigenvalue is above 1,the cumulative contribution rate is 63.632%.Conclusions： The questionnaire has a good reliability and validity,which can become a tool and scale to classify the syndromes of sub-health state.

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