中文摘要：

以大鼠为试验对象，设阴性对照（A）组和模拟低频与高频2种运输应激组。模拟应激组分别设为阳性对照（B）组、苯巴比妥（P）组和谷氨酰胺（Gin）组。A和B组每天灌胃生理盐水1mL·只^-1，P组和Gin组每天分别灌胃苯巴比妥15mg·（kg·只）^-1和Gin 500mg·（kg·只）^-1，10d后，除A组外，其他6组分别模拟低频和高频运输应激2h，然后测定所有试验鼠血清、组织中氨基酸含量的变化，探讨Gin对运输应激中大鼠的保护作用。结果表明：与A组相比，补充Gin后，低频或高频应激大鼠的血清、组织中与应激密切相关的氨基酸含量均无显著差异（P〉0．05），而与B组相比，所测氨基酸差异显著（P〈0．05）或差异极显著（P〈0．01）；镇静药物苯巴比妥对抗运输应激则没有效果。证明Gin具有保护大鼠抵抗运输应激的作用。

英文摘要：

Taken rats as experimental objects, the rats were randomly divided into negative control （A）, low frequency transport stress group and high frequency transport stress group. Each frequency stress group also included positive control group （B）, Phenobarbital group（P） and Gin group（Q）. Each rat in （A） and （B） group was oral administered with physiological saline （1 mL · d^-1 ）. The rats of P and Gin groups were oral administered with Phenobarbital 15 mg（kg · d）^-1 and Gin 500 mg · （kg · d）^ -1 ,respectively. After 10 d, rats in each group were vibrated under simulated low （L） and high frequency （H） transport stress for 2 hours except for （A） group, then all the rats were killed. Serum and tissues were collected and tested for the content of dissociative amino acid by RP-HPLC to find out the anti-stress effects of glutamine on rats. The results showed that compared with （A） group, significantly differences of the content of the amino acids related to stress in serum and tissues could not be found in rats treated with Gln（ P 〉 0. 05 ）, but the content of these animo acids was obviously higher than （B） group （P 〈 0. 05 or P 〈 0. 01 ）. And the narcotic of Phenobarbital did not show any effects on resisting transport stress. The results of this study proved that Gin can protect rats from transport stress.