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中文摘要：
介绍了在固体支持物表面固定DNA过程中使用的纳米颗粒的种类、固定方法及其特点。纳米颗粒巨大的比表面积及其与DNA良好的生物相容性可以增加DNA的固定量，改善杂化反应的识别能力，进而提高DNA传感器的检测灵敏度。
英文摘要：
Many nanoparticles can be used in the immobilization of DNA on the surface of the solid substrate. The species immobilization methods and characteristics of such nanoparticles are introduced. Both the quantity of immobilized DNA and the recognition property of the hybridization reaction can be greatly enhanced by the application of nanoparticles with large surface and good biocompatibility to DNA, and thus the detection sensitivity of the DNA sensors can be increased.
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