紫苏籽为唇形科植物紫苏[Perilla frutescens(L.)Britt]的干燥成熟果实,其味辛,性温,无毒,具有降气消痰、平喘、润肠的功效。许多研究表明紫苏具有降低血脂的作用,但主要着眼于富含α-亚麻酸的紫苏油,对直接食用紫苏籽是否具有调节血脂代谢及抗脂质过氧化作用,则鲜有报道。笔者从已有的研究基础出发,对紫苏籽调节血脂及抗脂质过氧化作用进行了研究。
[ Objective ] Study on the effect of perilla seed on blood lipid regulation and peroxidation of Coturnix coturnix with hyperlipidemia. [ Method ] The high-lipid.diet was fed to establish the high lipid model of Coturnix coturnix. The normal control group, high lipid model group, high dose of perilla seed group(2.5 g/kg), low dose of perilla seed group (0.83 g/kg) were designed to measure the contents of total cholesterol (TC), three acids glyceride (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), very low density lipoprotein cholesterol (VLDL-C) and malondialdehyde (MDA), superoxide dismutase (SOD) activity. [ Result] All the test groups could decrease TC ,TG,LDL-C and MDA content and significantly increase the HDL-C content (p 〈 0.01) and SOD activity(p 〈 0.01 ) in serum. [ Conclusion] Perilla seed has the blood lipid regulation and peroxidation function.