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IL-17 Contributes to Autoimmune Hepatitis
  • ISSN号:1674-0769
  • 期刊名称:《中国病毒学:英文版》
  • 时间:0
  • 分类:R575.1[医药卫生—消化系统;医药卫生—临床医学;医药卫生—内科学]
  • 作者机构:[1]Department of Infectious Disease Tongji Hospital Tongji Medical College Huazhong University of Science and Technology
  • 相关基金:supported by a grant from National "973" Project in viral hepatitis (MOST, No. 2007CB512900)
中文摘要:

The role of interleukin-17 (IL-17) in autoimmune hepatitis (AIH) was investigated. A mouse model of experimental autoimmune hepatitis was established, and the syngeneic S-100 antigen emulsified in complete Freud's adjuvant was injected intraperitoneally into adult male C57BL/6 mice. The IL-17 expression in serum and the livers of the mice models was detected by using ELISA and immunohistochemistry, respectively. IL-17 neutralizing antibody was used to study the biological effect of IL-17 in the experimental...

英文摘要:

The role of interleukin-17 (IL-17) in autoimmune hepatitis (AIH) was investigated. A mouse model of experimental autoimmune hepatitis was established, and the syngeneic S-100 antigen emulsified in complete Freud’s adjuvant was injected intraperitoneally into adult male C57BL/6 mice. The IL-17 expression in serum and the livers of the mice models was detected by using ELISA and immunohistochemistry, respectively. IL-17 neutralizing antibody was used to study the biological effect of IL-17 in the experimental...

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期刊信息
  • 《中国病毒学:英文版》
  • 中国科技核心期刊
  • 主管单位:中国科学院
  • 主办单位:中国科学院武汉病毒研究所 中国微生物学会
  • 主编:陈新文
  • 地址:湖北省武汉市武昌区小洪山中区44号
  • 邮编:430071
  • 邮箱:info@virosin.org
  • 电话:027-87199157
  • 国际标准刊号:ISSN:1674-0769
  • 国内统一刊号:ISSN:42-1760/Q
  • 邮发代号:38-351
  • 获奖情况:
  • 湖北省第1、2、3、4、5、6届优秀期刊,中国科学技术学会 优秀国际科技期刊,2012年中国国际影响力优秀学术期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),波兰哥白尼索引,荷兰医学文摘,美国生物医学检索系统,美国剑桥科学文摘,美国生物科学数据库,中国中国科技核心期刊
  • 被引量:208