中文摘要：

本试验通过与未包被氧化锌（ ZnO）对比,考察包被氧化锌（ C-ZnO）对断奶仔猪生长性能、血清生化指标、营养物质表观消化率影响,旨在研究C-ZnO取代传统ZnO的效果,对生产实践中减少ZnO用量的可能性和加强其效果的可能性进行探讨。选28日龄遗传背景相似、平均体重为（9.32±0.38） kg的断奶大白仔猪120头,随机分成5组,每组4个重复,每个重复6头猪（公母各占1/2）。对照组饲喂基础饲粮,试验组分别在基础饲粮中添加2400 mg/kg ZnO 和1800、2400、2760 mg/kg C-ZnO。试验期为28 d。结果表明：与对照组相比,饲粮中添加2400 mg/kg C-ZnO可极显著提高断奶仔猪的平均日增重（P〈0.01）,显著降低料重比（P〈0.05）,极显著降低腹泻率（ P〈0.01）,其中2400 mg/kg C-ZnO组的平均日增重极显著高于ZnO组（ P〈0.01）。与对照组相比,2400 mg/kg C-ZnO组血清生长激素、免疫球蛋白G、免疫球蛋白M含量极显著升高（ P〈0.01）；粗蛋白质和粗脂肪的表观消化率极显著改善（ P〈0.01）；大肠杆菌菌群数量极显著降低（ P〈0.01）,双歧杆菌菌群数量极显著升高（ P〈0.01）。2400 mg/kg C-ZnO组与ZnO组相比,血清生长激素含量显著提高（P〈0.05）,碱性磷酸酶活性显著降低（P〈0.05）。1800 mg/kg C-ZnO组与ZnO组生长性能、血清指标及营养物质表观消化率差异均不显著（ P〉0.05）。 ZnO组与对照组相比腹泻率显著降低（P〈0.05）,其他生长性能指标差异不显著（P〉0.05）。本研究结果提示：添加2400 mg/kg C-ZnO可显著提高断奶仔猪的生长性能,改善营养物质消化状况,有效控制仔猪腹泻；1800 mg/kg C-ZnO可替代2400 mg/kg ZnO。

英文摘要：

This trial was conducted to study the effects of coated ZnO （ C-ZnO） on the growth performance, the serum biochemical indices and nutrient apparent digestibility of weaner piglets, by compared with uncoated ZnO, aimed at research the effects of C-ZnO instead of traditional ZnO, and discussed production practice to reduce the possibility of the dosage of ZnO and enhance its effect. A total of 120 Large-White weaner piglets were randomly divided into 5 groups with 4 replicates per group and 6 piglets per replicate. Piglets in control group were fed a basal diet, the four groups were fed the basal diet supplemented with 2 400 mg/kg ZnO and 1 800, 2 400, 2 740 mg/kg C-ZnO, respectively. The trial lasted for 28 days. The results showed as follows：compared with control group, the average daily gain in the group supplemented with 2 400 mg/kg C-ZnO was increased significantly （ P〈0.01） , the ratio of feed to gain was decreased significantly （ P〈0.05） , and the di-arrhea rate was decreased significantly （ P〈0.01） . The average daily gain of 2 400 mg/kg C-ZnO group was significantly higher than that of ZnO group （ P〈0. 01 ） . Compared with control group, serum contents of growth hormone （ GH） , immunoglobulin G （ IgG） , immunoglobulin M （ IgM） and the digestibility of crude protein and ether extract were significantly increased in 2 400 mg/kg C-ZnO group （ P〈0.01） . Compared with control group, a significant reduction in E. coli number （ P〈0.01） and a significantly increase in Bifidobacteria number were also observed in 2 400 mg/kg C-ZnO group （ P〈0.01） . Compared with ZnO group, serum GH content was significantly increased （P〈0.05） and alkline phosphatase （AKP） activity was significantly de-creased （ P〈0.05） in 2 400 mg/kg C-ZnO group. There were no differences in the growth performance, serum indices and nutrients apparent digestibility between the 1 800 mg/kg C-ZnO and ZnO groups （ P〉0.05） . The diarrhea rate in ZnO groups was significantl