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中文摘要：
胃饥饿素又称作生长激素释放肽,最初是在大鼠的胃内被发现的,它是生长激素促分泌素受体1A（GHSR-1A）的一种内源性配体。在下丘脑弓形核（ARC）及室旁核（PVN）高度表达GHSR-1A的区域,胃饥饿素结合GHSR-1A后,产生一系列生物学效应。本文综述了胃饥饿素的生物学特征及功能、对动物采食量调控的机制、影响胃饥饿素基因表达调控的因素和反馈抑制以及前景展望。
英文摘要：
Ghrelin,also known as growth hormone releasing peptide,is originally discovered in the stomach of rats,and it is an endogenous ligand of growth hormone secretagogue receptor-1A（ GHSR-1A）. In the hypothalamic arcuate nucleus（ ARC） and paraventricular nucleus（ PVN）,G HSR-1A is highly expressed. In these areas,ghrelin has a series of biological effects after combining GHSR-1A. This paper reviewed biological characteristics and functions,the regulation mechanism on animal feed intake,factors influencing gene expression and modulation,feedback inhibition of ghrelin,and gave outlooks for researches into ghrelin in the future.
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