中文摘要：

目的：研究不孕妇女细菌性阴道病（ Bacterial vaginal disease ，BVD）与四种自身抗体的相关性探讨。方法：从2012年5月至2013年5月，选择我院299例不孕患者作为研究对象，根据患者病情进行分组，原发性不孕（Primary infertility，PI）组94例，人流后继发性不孕（Secondary infertility after induced abortion，SIAIA）组103例，药流后继发性不孕（Secondary infertility after medicine flows ，SIAMF）组102例。另选100例健康体检的女性为对照组，对比各组患者BVD阳性率情况，血清四种抗体的检测结果并分析BVD与抗体的相关性。结果：PI组、SIAIA组与SIAMF组的BVD阳性率均显著高于对照组，差异均有统计学意义（均P＜0．05）。 PI BVD 阳性组的AsAb阳性率为34．48％（10/29），显著高于PI BVD阴性组的13．85％（9/65），差异有统计学意义（P＜0．05）。 SIAIA BVD阳性组的EmAb阳性率为45．16％（14/31），显著高于SIAIA BVD阴性组的24．66％（18/73），差异有统计学意义（P＜0．05）。SIAMF BVD阳性组与SIAMF BVD阴性组在AsAb阳性率、EmAb阳性率、ACA阳性率以及AzpAb阳性率等方面对比，差异均无统计学意义（均P＞0．05）。 BVD与PI AsAb 以及SIAIA EmAb 均呈正相关。结论：不孕妇女BVD发生率较高，且和PI AsAb以及SIAIA EmAb具有较强相关性，值得临床关注。

英文摘要：

Objective：To study correlation exploration of infertile women with bacterial vaginal disease （BVD） and four kinds of autoantibodies .Method：From May 2012 to May 2013, in our hospital, 299 cases of infertility patients as research subjects , They were divided into groups according to the patient＇s condition , with primary infertility （ PI） group of 94 cases , the secondary infertility after induced abortion group （ SIA-IA） of 103 cases, the secondary infertility after medicine flows （SIAMF） group of 102 cases.Chose another 100 cases of healthy women as a control group , and then compared each group of BVD positive rate , test re-sults of four antibodies in serum , and analyzed the correlation with BVD antibodies .Result： BVD positive rate of PI group, SIAIA group and SIAMF group was significantly higher than PI BVD group , the differences was statistically significant （ P 〈0.05）.PI BVD group’s AsAb positive rate was 34.48%（ 10/29 ）, signif-icantly higher than PI BVD negative group （9/65） 13.85%, the difference was statistically significant （P 〈0.05） .EmAb positive rate of SIAIA BVD positive group was 45.16%（ 14 /31 ） , significantly higher than SIAIA BVD negative group （ 18/73） 24.66%, the difference was statistically significant （ P 〈0.05） .SIAMF BVD positive group and negative group was contrasted in AsAb positive rate , EmAb positive rate , ACA posi-tive rate and AzpAb positive rate , the difference was not statistically significant （ P〉0.05）.BVD with PI AsAb and SIAIA EmAb had positive correlation .Conclusion： The infertile women has higher BVD inci-dence, and with PI AsAb and SIAIA EmAb has a strong correlation .Which is worthy of attention .