中文摘要：

目的 探讨益生菌改善高龄老年慢性心力衰竭患者心功能和生活质量的有效性.方法 选取50名高龄老年慢性心力衰竭患者,随机分为益生菌组和安慰剂对照组.均在接受常规抗心力衰竭药物治疗基础上,益生菌组加用益生菌4个月,安慰剂对照组则给予安慰剂.4个月后采用超声心动图测定左心室射血分数,并对患者进行生活质量评分等.结果 接受益生菌治疗的患者,和基线值相比,试验终点左心室射血分数和生活质量评分增加,与安慰剂组相比,益生菌组患者的左心室射血分数和生活质量评分增加值显著提高.结论 在常规抗心力衰竭治疗药物的基础上,口服益生菌可以明显改善高龄老年慢性心力衰竭患者的左心室功能和生活质量.

英文摘要：

Objective To investigate the efficacy of probiotics in improving the cardiac function and quality of life in elderly patients with chronic heart failure. Methods 50 elderly patients with chronic heart failure were randomly divided into two groups. On the basis of conventional anti heart failure drugs ,the probiotic group was treated with probiotics for 4 months ,and the control group was given a placebo.4 months later,the left ventricular ejection fraction was assessed by echocardiography,and the quality of life scores were assessed. Results Left ventricular ejection fraction and quality of life score increased significantly in patients treated with probiotics compared with baseline.The left ventricular ejection fraction and the quality of life score increased significantly in the probiotic group compared with the placebo group. Conclusion On the basis of conventional anti heart failure drugs ,oral probiotic therapy can significantly improve left ventricular ejection fraction and quality of life in elderly patients with chronic heart failure.