研究了人工骨微管道中细胞和细胞悬液的速度场、细胞浓度分布,并分析了细胞在微管道中可能沉积的部位。研究表明,在该微管道系统的模拟哈佛氏管和佛克曼管交叉处附近细胞浓度较高,离管壁0.3r处细胞浓度最大。离管壁一定距离处存在细胞相速度大于液相速度的过渡区域,该过渡区域内存在扩散作用和细胞亲壁生物特性,使得部分细胞沉积于管壁,过渡区域外的主流区细胞相速度小于液相速度,但大部分细胞将被液相带走。
The velocity fields and cell volume concentration distribution in microtubules of artificial bone were studied. On the basis of these, the spots of cell deposition were analyzed. The results indicate that the most concentration spots are near the joint of Halverson Canal and Volkmann Canal and the location is on about 0.3r(radius) from centerline to the bottom of microtubules. The speed of cell-phase is higher than that of liquid phase in certain transition zone. In the zone of proximal tube wall, some of the cells will deposit on the wall because of the diffusion and adhesiveness of the cells. In the zone of main stream, the speed of cell-phase is lower than that of liquid phase, but most of the cells will be dragged by the liquid.