目的观察针刺配合高压氧治疗脑卒中后抑郁症的临床疗效。方法将120例脑卒中后抑郁症患者随机分为治疗组60例和对照组60例,治疗组予针刺配合高压氧治疗,对照组予氟西汀胶囊(百优解)治疗。治疗前及治疗14 d、28 d后分别采用汉密尔顿抑郁量表(HAMD)及神经功能缺损量表(NIHSS)对患者进行评定,比较两组的疗效。结果治疗组疗效明显优于对照组(P〈0.01)。治疗1个疗程后,两组HAMD及NIHSS评分均有下降,治疗组与治疗前比较差异有统计学意义(P〈0.01),但对照组与治疗前比较差异无统计学意义(P〉0.05)。治疗2个疗程后,两组HAMD及NIHSS评分与治疗前比较差异均有统计学意义(P〈0.01),且治疗组下降更明显(P〈0.01)。结论针刺配合高压氧治疗脑卒中后抑郁症明确有效,而且能明显改善神经功能。
Objective To observe the clinical efficacy of acupuncture plus hyperbaric oxygen in treating depression after cerebral stroke. Method A total of 120 patients with depression after cerebral stroke were randomized into a treatment group of 60 cases and a control group of 60 cases. The treatment group was intervened by acupuncture plus hyperbaric oxygen, while the control group was intervened by Fluoxetine. Before the treatment, and respectively after 14-d and 28-d treatments, the patients were evaluated by Hamilton Depression Scale(HAMD) and National Institute of Health Stroke Scale(NIHSS), and the therapeutic efficacies were compared between the two groups. Result The treatment group was significantly superior to the control group in comparing therapeutic efficacy(P〈0.01). After 1 course of treatment, the HAMD and NIHSS scores dropped significantly in the treatment group(P〈0.01); the scores in the control group showed a declining tendency but without statistical significances(P〈0.05). After 2 treatment courses, the HAMD and NIHSS scores were significantly different from those before the treatment in both groups(P〈0.01), and the differences were more significant in the treatment group(P〈0.01). Conclusion Acupuncture plus hyperbaric oxygen is effective in treating depression after cerebral stroke, and it can obviously improve the neural function.