中文摘要：

研究了从硬枝树花中提取得到的4个单体化合物松萝酸（usnic acid）、去甲环萝酸（evernic acid）、巴尔巴地衣酸（barbatic acid）和水杨嗪酸（salazinic acid）对H22荷瘤小鼠的抑瘤作用,并且对抑瘤率、胸腺指数、脾指数及小鼠白介素-2含量等各个指标的进行检测,以说明此4种化合物对小鼠肿瘤生长的抑制效果。结果表明,松萝酸高、中剂量组,去甲环萝酸高、中剂量组,巴尔巴地衣酸低剂量组,水杨嗪酸高剂量组对小鼠肿瘤有较好的抑制效果,与阴性对照组比较有极显著差异（P〈0.01）,并且这些组的H22荷瘤小鼠血清中白介素-2的含量显著增加,与抑制肿瘤活性具有相关性。

英文摘要：

The anti-tumor activities of usnic acid, evernic acid, barbatic acid and salazinic acid extracted from thallus of Ramalina conduplicans were studied. The anti-tumor rate, and thymus and spleen indexes were calculated and the content of serum IL-2 were detected. The results showed that usnic acid [20mg/（kg.d）, 10mg/（kg.d）], evernic acid [20mg/（kg.d）, 10mg/（kg.d）], barbatic acid [5mg/（kg.d）], and salazinic acid [20mg/（kg.d）] had obviously inhibitory effect on the tumor in H22 mice. The anti-tumor rate of these compounds were obviously higher than that of negative control （P〈0.01）. These four compounds can influence thymus and spleen indexes and the content of serum IL-2 in treated H22 mice was significantly higher than that in negative and control （P〈0.01）.