中文摘要：

目的分析不同输入动脉所得鼻咽癌（NPC）多层螺旋CT灌注参数值的差异。方法对38例经病理确诊的初发NPC患者进行CT灌注扫描,每例患者均分别选择肿瘤同侧的颈内动脉（ICA组）和颈外动脉（ECA组）作为输入动脉、颈内静脉作为输出静脉进行灌注成像后处理,获得两组灌注参数。采用配对t检验分析两组灌注参数值的差异,并对两组数据进行直线相关分析。结果两组不同血管所得灌注参数值差异均无统计学意义（P〉0.05）,两组数据血流量、血容量、平均通过时间和表面通透性的相关系数分别为0.879、0.630、0.525、0.695（P均〈0.001）,两组血管所得数据均成正相关。结论在对NPC患者进行CT灌注成像后处理时,可根据患者血管的显示情况选择颈内动脉和（或）颈外动脉作为输入动脉。

英文摘要：

Objective To observe the difference of multi-slice spiral CT perfusion parameters in different reference arteries in diagnosis of nasopharyngeal carcinoma（NPC）.Methods Thirty-eight patients with NPC underwent CT perfusion imaging,internal carotid artery（ICA group） and external carotid artery（ECA group） were selected respectively as reference artery with CT perfusion imaging post-processing in each patient.The differences of perfusion parameters between the two groups were analyzed with paired-samples t test and linear correlation.Results Parameters derived from ICA and ECA as reference artery were not statistically different（all P〉0.05）.There were positive correlation of all parameters between both groups,the correlation coefficients was 0.879 for blood flow,0.630 for blood volume,0.525 for mean transit time and 0.695 for permeability surface（all P〈0.001）.Conclusion On the post-processing of CT perfusion imaging for NPC,internal carotid artery and external carotid arteries can both be selected as the reference artery according to their displaying.