目的探讨高同型半胱氨酸血症与高血压早期肾损害的关系。方法将2012年7月-2014年7月收治的高血压病患者108例及健康对照组50例均测定血清同型半胱氨酸水平、血糖、肾功能、血清胱抑酶C。结果高血压中肾功能改变者49例,高血压组的血清同型半胱氨酸平均水平明显高于健康对照组(P〈0.05),血清同型半胱氨酸与血清胱抑酶C间存在正相关性(P〈0.05)。结论血清同型半胱氨酸联合血清胱抑酶C能够早期判断高血压肾脏损害。
Objectives To study the relationship betweenhyperhomocysteinemia and early renal damage in essential hyperten-sion.Methods 108 cases with hypertension from 2012 July to 2014 July in our hospital and healthin the control group of 50 cases were measured serum levels of homocysteine,blood glucose,renal function,serum cystain C enzyme inhibition.Results The changes of renal hypertension in 49 cases,accounting for 45.37% of the hypertensive group,the serum homocysteine level was significantly higher than that in healthy control group(P〈0.05).There is a positive correlation between serum homocysteine and serum cystatin inhibitory C ( P〈0.05) .Conclusions The serum cystine cysteine combined with anti enzymeC can determine the early hyperten-sive renal damage.