东篱科研大数据发现系统（DRDS）

位置：成果数据库 > 期刊 > 期刊详情页

帕金森病老年患者便秘症状的临床研究

ISSN号：1672-4860
期刊名称：《中国老年保健医学》
时间：0
分类：R574.62[医药卫生—消化系统;医药卫生—临床医学;医药卫生—内科学]
作者机构：[1]广西壮族自治区江滨医院神经内科,530002, [2]北京医院、国家老年医学中心、卫生部老年医学重点实验室,100730
相关基金：国家自然科学基金（81061120527,81370445,81472408）; 卫生部公益性研究基金（201302008）; 国家科技部十二五支撑计划（2012BAI10B01,2015BAI06B00）; 广西自然科学基金重点项目“LOAD关联基因联合检测的效应分析及其分子机理研究”（项目编号：2014GXNSFDA118028）

作者：何香花[1], 庞国防[1], 梁庆华[1], 杨泽[2], 胡才友[1]

关键词：帕金森病, 便秘, 非运动症状, Parkinson＇s disease, constipation, non-motor symptoms

中文摘要：

目的探讨广西地区帕金森病（PD）患者便秘的临床特点。方法选取我院门诊或住院部连续的PD患者141例,根据是否便秘又分为便秘组和非便秘组（其中便秘组76例,非便秘组65例）。收集各组临床资料,采用PD综合评分量表第3部分（UPDRSⅢ）评分、H-Y分期量表（H-Y）对患者进行测评和比较。结果 76例便秘患者中,28例（36.8%,28/76）患者的便秘症状先于运动症状出现。便秘组和非便秘组性别分布（P=0.811）和起病年龄差异无统计学意义（P=0.646）。与非便秘组相比,便秘组的病程长、UPDRSⅢ评分高、H-Y分期高（所有P〈0.05）。结论广西地区PD患者的便秘发生率较高。便秘症状先于运动症状出现的比例较高,提示便秘可能是PD的早期症状。

英文摘要：

Objectives To investigate the chnical characteristics of constipation in patients with Parkinson＇s disease （PD） in Guangxi province. Methods A total of 141 patients with PD were enrolled in this study. According to whether constipation was divided into constipation group and non-constipation group （ including 76 cases with constipation and 65 cases without constipation）. The clinical data were collected and the patients were evaluated and compared by using the UPDRS Ⅲ score and the H-Y staging scale （H-Y）. Results 28 patients （36. 8% , 28/76） of the 76 patients with constipation had symptoms before exercise symptoms occurred. There was no significant difference in the sex distribution between the constipation group and the non-constipation group （ P = 0. 811 ） and the age of onset （ P = 0. 646）. Compared with the non-constipation group, the course of the constipation group was longer, the UPDRS m score was higher and the H-Y stage was higher （all P 〈 0. 05）. Conclusion Constipation symptoms before the occurrence of a higher proportion of motor symptoms, suggesting that constipation may be early symptoms of PD.

同期刊论文项目