目的:阐述代谢组学技术的优势,促进代谢组学技术在体质研究中的应用。方法:介绍中医体质的影响因素与代谢组学及其研究优势,论述代谢组学在中医体质学研究中的应用方向及代谢组学方法应用进展。结果:拓展中医体质研究思路和方法,加快传统中医药与现代生命科学技术的结合,推动中医药现代化,为中医药的发展提供新的空间。结论:代谢组学技术原理与中医体质理论和诊疗思维有异曲同工之处,在整体观及动态变化状态上具有相似性,运用代谢组学方法进行体质可分、体病相关等中医体质关键科学问题的研究,为探索中医药理论的现代研究提供了新的支撑。
Objective: To summarize the advantages of metabonomics technology and promote its application in the study of physical constitution. Methods: It is stated that the effective factors of traditional Chinese medical constitution and the progress of metabonomics technology in the study of physical constitution. Results: The research mentality and technique of traditional Chinese medical constitution were expanded. It could accelerate the combination of traditional Chinese medicine and modern biotechnology. As a result,modernization of traditional Chinese medicine could be driven. Conclusion: There is something in common between the theory of metabonomics technology and theory of traditional Chinese medical constitution,such as the holism and the dynamic variation. The metabonomics technology is used to study the classification of constitution and the relationship between constitution and disease. It is significant for the modernization of theories of traditional Chinese medicine.