中文摘要：

目的观察中药黄芪注射液对外伤性脾破裂行脾切除患者手术前、后外周血T淋巴细胞亚群的变化。方法选50例外伤性脾破裂需要行脾切除病例，随机分实验组、对照组，每组各25例。用免疫荧光法检测脾切除患者手术前、术后第1、3、7d测定T细胞亚群CD3、CD4、CD8数值水平，分别记录实验组、对照组切口感染、肺部感染、术后低热的发生率。结果实验组、对照组术前外周血CD3、CD4、CD8水平比较无统计学意义。脾切除术后第1d，CD3、CIM、CD8水平较手术前比较，两组均有降低，组间比较无统计学意义；但实验组第3d呈升高趋势，且第7d仍然保持在较高水平。对照组第3d即下降，第7d与第3d比较，变化无统计学意义。两组在术后第3d开始，CD3、CD4、CD8数据比较即有明显差异（P〈0．05）。结论黄芪注射液对脾切除术后早期T细胞亚群CD3、CIM、CD8水平的变化，具有一定影响，对脾切除术后免疫功能的提高、术后并发症的减少，具有较好的疗效，可以作为脾切除术后中西医结合提高患者免疫功能的一种治疗手段。

英文摘要：

Objective Observed before traumatic rupture of traditional Chinese medicine Huangqi injection on patients undergoing splenectomy after peripheral blood T lymphocyte subsets. Method 50 cases of traumatic rupture of the need splenectomy patients were randomly divided into experimental group and control group, 25 cases in each group. By immunofluorescenceassay before splenectomy surgery patients,post operative1,3 ,Tday measured T cell subsets CD3, CD4, CD8 numerical level. Were recorded in the experimental group and control group wound infection, pulmonary infection, the incidence of postoperative fever. Results the experimental group, control group preoperative peripheral blood CD3, CD44, CD8 level was not statistically significant. Splenectomy Section post operativel day, CD3, CD4, CD8 levels than before the surgery compared both groups decreased between the two groups was not statistically significant;However, the experimental groups howed an increasing trend after operative 3day, and the after operative 7 day remained at a high level, after operative 3 day control group that dropped, and the after 7day,3day comparison with the T cell change was not statistically significant. The two groups began in the 3 days after surgery, CD3, CD4, CD8 data comparisons that were significantly different （P 〈 0. 05）. Conclusion Huangqi injection on splenectomy early T cell subsets CD3, CD4, CD8 level changes, Has a certain influence, Improve immune function .reduce immune function after splenectomy post operative complications, with good effect, Huangqi injection could be a treatment of combine traditional Chinese and western medicine to improveimmune function inpatients aftersplenectomy.