以5-氟尿嘧啶-1-基乙酸、二环己基碳二酰亚胺和L-苯丙氨酸为原料,1-羟基苯并三氮唑作为辅助试剂,通过碳二亚胺法合成了-种新型的理-(5-氟尿嘧啶-1-基甲基甲酰基)氨基苯丙酸,其结构经IR和元素分析表征。
A novel α- { [ ( 5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1-2H-yl ) acetyl ] amino } benzylpropanoie acid was synthesized by earbodiimide method from 5-fluorouraeil-1-yl acetic acid, N,N'-dieyelohexylearbo-diimide and L-phenylalanine using 1-hydroxybenzotrizole as an auxiliary reagent. The structure was characterized by IR and elemental analysis.