近年来,白细胞介素10(IL-10)与莱姆病的关系及其相关机制是目前研究的热点问题。如何利用IL-10的抗炎作用及对炎症的调控而对莱姆病采取积极有效的预防、治疗措施是近来研究的焦点。本文概述了白介素-10在莱姆病中的作用及其机制方面的研究进展。
Current studies are interested in the role of IL-10,a type of anti-inflammatory cytokine,in Lyme disease and its mechanism of action.Recent studies have focused on possible use of the anti-inflammatory action of and modulation of inflammation by IL-10 to actively and effectively prevent and treat Lyme disease.IL-10 and Lyme disease are reported to be related.To the extent known,however,few systematic studies have reported on the effect of IL-10 on Lyme disease,let alone on the detailed mechanism responsible.This paper reviews the effect of IL-10 on Lyme disease and its mechanism of action in order to provide new insight into the pathogenesis of Lyme disease and its treatment via an IL-10 intervention.