目的总结术中超声辅助神经导航系统在颅内胶质瘤手术中的应用经验。方法回顾性分析自2010年1月至2013年6月安徽医科大学附属省立医院经术中超声辅助神经导航手术的60例患者的临床资料,其中高级别胶质瘤32例、低级别胶质瘤28例。观察不同级别脑胶质瘤超声图像的表现。结果术中超声辅助神经导航定位肿瘤位置的准确性100%。病灶超声图像中,高级别胶质瘤术中超声显示明显高回声且边界通常清楚,低级别多显示略高回声或接近等回声,通常边界稍模糊;病灶切除前显示不均匀高回声,切除完后显示低回声残腔影信号。手术后影像学证实肿瘤全切除50例,大部分切除6例,部分切除4例。术后脑肿胀1例.行去骨瓣减压术后缓解;术后偏瘫2例;无死亡病例。结论术中超声可以纠正脑移位,其为术者选择何种手术人路、何处切开皮层等方面提供了明确且价值重要的依据。术中超声显示高级别胶质瘤和钙化病变边界最好。术中超声辅助神经导航有助于提高颅内胶质瘤的切除率。
Objective To conclude the application experience of intraoperative ultrasound added with neuronavigation in resection of intracranial gliomas. Methods A retrospective analysis was performed on the clinical data of 60 patients with intracranial gliomas, performed resection in our hospital from January 2010 to June 2013 by intraoperative ultrasound added with neuronavigation; 32 of them had high-grade gliomas and 28 low-grade ones. Ultrasonoscopy of different grade gliomas was studied. Resdts The accuracy of localization was 100% in 60 patients with intracranial gliomas. Ultrasonic image of high-grade gliomas enjoyed obvious hyperechogenicity and the boundaries were clear usually; ultrasonic image of low-grade ones were slightly hyperechogenic or isoechogenic and the boundaries were indistinct usually. Inhomogeneous hyperechogenic of the ultrasonoscopy of intracranial gliomas before resection and hypoechogenic of residual cavity after resection were noted, respectively. Total removal was achieved in 50 patients, subtotal resection in 6 and partial resection in 4. Brain swelling happened postoperatively in 1 and was remitted by decompressive craniectomy. Hemiplegia happened in 2, and no death occurred postoperatively. Conclusions Intraoperative ultrasound is important to the correct of brain shift, and has clear and important value to the choice of operation approach and incising cortex. Ultrasonic image of high-grade gliomas and calcified lesions enjoys the best view. Intraoperative ultrasound added with neuronavigation can raise resection rate of intracranial gliomas.