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中文摘要：
围绕生物分子的高灵敏、高选择性的快速传感分析，近两年实验室结合多种纳米技术，利用制备和获得的先进纳米材料，研制了一系列电化学生物传感器，包括安培传感器、电容传感器和电致化学发光传感器，用于过氧化氢、溶解氧、NO、NADH、脱氢酶底物（乙醇）、氧化酶底物（葡萄糖）、谷胱甘肽和L-半胱氨酸等OH^＊自由基湮灭剂、苯醌类物质、蛋白质等多种生物分子的分析检测。主要包括如下内容：
同期刊论文项目
同项目期刊论文
Theoretical study of the interaction pattern and the binding affinity between procaine and DNA bases
Effect of enteral nutrition formula on fat absorption and serum free fatty acid profiles in rat with
Zirconia nanoparticles enhanced grafted collagen tri-helix scaffold for unmediated biosensing of hyd
Simultaneous determination of ethamsylate, tramadol and lidocaine in human urine by capillary electr
Novel coupling mechanism-based imaging approach to scanning electrochemical microscopy for probing t
Off-line form of the Michaelis-Menten equation for studying the reaction kinetics in a polymer micro
Microchannel-electrode alignment and separation parameters comparison in microchip capillary electro
Synthesis of metallic nanoparticles protected with N,N,N-trimethyl chitosan chloride via a relativel
Gold nanoparticles doped three-dimensional sol-gel matrix for amperometric human chorionic gonadotro
Simultaneous determination of psychotropic drugs in human urine by capillary electrophoresis with el
Flow-injection chemiluminescent immunoassay for alpha-fetoprotein based on epoxysilane modified glas
Electrogenerated chemiluminescence detection of amino acids based on precolumn derivatization couple
Multilayer membranes for glucose biosensing via layer-by-layer assembly of multiwall carbon nanotube
A gold nanoparticles/sol-gel composite architecture for encapsulation of immunoconjugate for reagent
Simultaneous electrochemiluminescence determination of sulpiride and tiapride by capillary electroph
A disposable electrochemical immunosensor for flow injection immunoassay of carcinoembryonic antigen
Electrochemical immunoassay of human chorionic gonadotrophin based on its immobilization in gold nan
Electrochemical study on synergistic effect of the blending of nano TiO2 and PLA polymer on the inte
Synergistic enhancement effect of magnetic nanoparticles on anticancer drug accumulation in cancer c
Noncovalent axial assembly of Picket-fence porphyrin on nitrogen-doped carbon nanotubes for highly e
Pretreatment-free fast ultraviolet detection of melamine in milk products with a disposable microflu
Determination, characterization and cytotoxicity on HELF of ZnO nanoparticles as ultraviolet screens
Simultaneous fabrication of through-hole porous membrane and nanotubes array in a single step anodiz
New anthracene–tetrathiafulvalene derivative-encapsulated SWNT nanocomposite and its application for
Quantum dot-functionalized poly(styrene-co-acrylic acid) microbeads: stepwise self-assembly, charact
Streptavidin-Functionalized Three-Dimensional Ordered Nanoporous Silica Film for Highly Efficient Ch
Dendritic silver/silicon dioxide nanocomposite modified electrodes for electrochemical sensing of hy
A chemiluminescent immunosensor based on antibody immobilized carboxylic resin beads coupled with mi
A channel-resolved approach coupled with magnet-captured technique for multianalyte chemiluminescent
Multipoint quantification of multimarker genes in peripheral blood and micrometastasis characteristi
Electrochemical study of the effect of functionalized nickel nanoparticles on cellular uptake of leu
Blends of TiO2 nanoparticles and poly (N-isopropylacrylamide)-co-polystyrene nanofibers as a means t
Channel-resolved multianalyte immunosensing system for flow-through chemiluminescent detection of al
A simple electrochemical method for the determination of hydroxyl free radicals without separation p
Electrochemical deposition and mechanism investigation of Prussian blue on graphic carbon paste elec
Surface electric field manipulation of the adsorption kinetics and biocatalytic properties of cytoch
Electrochemical determination of NDPhA via its electrocatalysis at porous Au electrode in room tempe
Improved separation efficiency of neurotransmitters on a native printed capillary electrophoresis mi
Electrochemically deposited nanocomposite film of CS-Fc/Au NPs/GOx for glucose biosensor application
Determination of nitrite based on its quenching effect on anodic electrochemiluminescence of CdSe qu
Highly sensitive amperometric biosensors for phenols based on polyaniline-ionic liquid-carbon nanofi
Direct Electrochemistry of Hemoglobin Immobilized on Colloidal Gold-Hydroxyapatite Nanocomposite for
Functionalization of Carbon Nanotubes with Water-Insoluble Porphyrin in Ionic Liquid: Direct Electro
Composition and Shape Control in the Construction of Functional Nickel Hexacyanoferrate Nanointerfac
One-step pyrolysis method for the synthesis of highly efficient 3D hollow carbon nanostructure suppo
Enhanced electrochemiluminescence efficiency of Ru(II) derivative covalently linked carbon nanotubes
A simple method for fabrication of sole composition nickel hexacyanoferrate modified electrode and i
Effect of surface microstructures on the separation efficiency of neurotransmitters on a direct-prin
Direct electrochemistry and electrocatalysis of hemoglobin on nanostructured gold colloid-silk fibro
Highly sensitive detection of daunorubicin based on carbon nanotubes–drug supramolecular interaction
Anodic electrochemiluminescence of CdSe nanoparticles coreacted with tertiary amine and halide induc
Addition of ethynylferrocene to transition-metal complexes containing a chelating 1,2-dicarba-closo-
Rapid identification and high sensitive detection of cancer cells on the gold nanoparticle interface
Study on the enhanced cellular uptake effect of daunorubicin on leukemia cells mediated via function
Application of the blending of PNIPAM- co -PS nanofibers with functionalized Au nanoparticles for th
Synergistic effect of functionalized nickel nanoparticles and quercetin on inhibition of the SMMC-77
Highly resolved separation and sensitive amperometric detection of amino acids with an assembled mic
Amperometric glucose sensor based on catalytic reduction of dissolved oxygen at soluble carbon nanof
Accelerated direct electrochemistry of hemoglobin based on hemoglobin-carbon nanotube (Hb-CNT) assem
The application of Fe3O4 nanoparticles in cancer research: A new strategy to inhibit drug resistance
Electrochemical DNA biosensor for the detection of short DNA species of Chronic Myelogenous Leukemia
Study of the nonenzymatic glucose sensor based on highly dispersed Pt nanoparticles supported on car
Functional multiwalled carbon nanotube nanocomposite with iron picket-fence porphyrin and its electr
Anodic electrochemiluminescence of CdTe quantum dots and its energy transfer for detection of catech
A disposable two-throughput electrochemical immunosensor chip for simultaneous multianalyte detennin
Enzyme-quantum dots architecture for highly sensitive electrochemiluminescence biosensing of oxidase
Detection of NADH and ethanol based on catalytic activity of soluble carbon nanofiber with low overp
A disposable multianalyte electrochemical immunosensor array for automated simultaneous determinatio
Sensitive reagentless electrochemical immunosensor based on an ormosil sol-gel membrane for human ch
An amperometric immunosensor for separation-free immunoassay of CA125 based on its covalent immobili
A disposable impedance sensor for electrochemical study and monitoring of adhesion and proliferation
One-step immobilization of glucose oxidase in a silica matrix on a Pt electrode by an electrochemica
Simultaneous electrochemiluminescence detection of anisodamine, atropine, and scopolamine in Flos da
Amperometric biosensor for hydrogen peroxide based on myoglobin doped multiwalled carbon nanotube en
Circulating tumor cells in perioperative esophageal cancer patients: Quantitative assay system and p
Highly sensitive flow injection detection of hydrogen peroxide with high throughput using a carbon n
A bio-inspired support of gold nanoparticles-chitosan nanocomposites gel for immobilization and elec
Reagentless biosensor for hydrogen peroxide based on immobilization of protein in zirconia nanoparti
Conductive mesocellular silica-carbon nanocomposite foams for immobilization, direct electrochemistr
Immobilization and electrochemical behavior of gold nanoparticles modified leukemia K562 cells and a
Hydrogen peroxide biosensor based on hemoglobin modified zirconia nanoparticles-grafted collagen mat
Highly efficient and of selective enrichment phosphopeptides using porous anodic alumina membrane fo
The synergistic effect of Prussian-Blue-grafted carbon nanotube/poly(4-vinylpyridine) composites for
Hydrogen bubble dynamic template synthesis of porous gold for nonenzymatic electrochemical detection
Superhydrophobicity of 3D porous copper films prepared by using the hydrogen bubble dynamic template
Amperometric sensor for ethanol based on one-step electropolymerization of thionine-carbon nanofiber
Al2O3/SnO2Co-nanoparticle modified grafted collagen for improving thermal stability and infrared emi
The effect of UV irradiation on the binding of anticancer drug doxorubicin to DNA in the presence of
DNA binding behavior of doxorubicin based on photovoltaic effect of nano titanium dioxide modified e
The enhancement effect of gold nanoparticles to facilitate the drug delivery and biomarker of drug-r
Magnetic controllable biorecognition process of doxorubicin detected by electrochemical contact angl
Amperometric detection of carbohydrates with a portable silicone/quartz capillary microchip by desig
Electrochemiluminescence sensors for scavengers of hydroxyl radical based on its annihilation in CdS
One-step pyrolysis process to synthesize dispersed Pt/carbon hollow nanospheres catalysts for electr
Cascade Signal Amplification Strategy for Subattomolar Protein Detection by Rolling Circle Amplifica
Comparative evaluation of the protective potentials of human paraoxonase 1 and 3 against CCl4-induce
Studies on protective effects of human paraoxonases 1 and 3 on atherosclerosis in apolipoprotein E k
A simple electrochemical lectin-probe for in situ homogeneous cytosensing and facile evaluation of c
A facile scanometric strategy for ultrasensitive detection of protein using aptamer-initiated rollin
Real-time monitoring of cell viability by its nanoscale height change with oxygen as endogenous indi
CuO-Doped Mesoporous Silica Hybrid for Rapid and Sensitive Amperometric Detection of Phenolic Compou
Ultrasensitive scanometric protocol for detection of matrix metalloproteinases using histidine tagge
In situ assembly of gold nanoparticles on nitrogen-doped carbon nanotubes for sensitive immunosensin
Noncovalent functionalization of carbon nanotubes with lectin for label-free dynamic monitoring of c
Disposable reagentless electrochemical immunosensor array based on a biopolymer/sol-gel membrane for
Electric field-driven strategy for multiplexed detection of protein biomarkers using a disposable re
Coreactant enhanced anodic electrocherniluminescence of CdTe quantum dots at low potential for sensi
Sampling-resolution strategy for one-way multiplexed inummoassay with sequential chemiluminescent de
Noncovalent nanoassembly of porphyrin on single-walled carbon nanotubes for electrocatalytic reducti
Effective cell capture with tetrapeptide-functionalized carbon nanotubes and dual signal amplificati
Facile synthesis and application of highly luminescent CdTe quantum dots with an electrogenerated pr
A disposable two-throughput electrochemical immunosensor chip for simultaneous multianalyte determin
Channel-resolved multianalyte immunosensing system for flow-through chemiluminescent detection of α-
Selective detection of glucose with wide concentration range by bienzyme channeling based on co-entr
Functional mutilwalled carbon nanotube nanocomposite with iron picket-fence porphyrin and its electr
Ultrasonic-assisted size-controllable synthesis of Bi2Te3 nanoflakes with electrogenerated chemilumi
Triterpenoids from Cimicifugae rhizoma, a novel class of inhibitors on bone resorption and ovariecto
Hemoglobin on phosphonic acid terminated self-assembled monolayers at gold electrode: immobilization
Enhanced solid-state electrochemilumi- nescence of CdS nanocrystals composited with carbon nanotubes
Enzyme-quantum dots architecture for highly sensitive electrochemilumines- cence biosensing of oxida
Highly Efficient and Selective Enrichment of Phosphopeptides Using Porous Anodic Alumina Membrane fo
Theoretical investigations of the geometric and electronic structures of phenylene-acetylene macrocy
Length-Dependent Conductance of Molecular Wiresand Contact Resistance in Metal–Molecule–Metal Juncti
Synthesis, characterization and immobilization of Prussian blue modified Au nanoparticles:applicatio
Synergistic effect of Prussian blue grafted carbon nanotubes/poly(4-vinylpyridine) composites for se
Template-Synthesized Protein Macroporous Biofilms Electrode: Conformational Related Electron Transfe
Characterization of plant growth-promoting rhizobacteria using capillary isoelectric focusing with w
Simultaneous determination of etamsylate, tramadol and lidocaine in human urine by capillary electro
Highly resolved separation and sensitive amperometric detection of amino acids with a flexible micro
Small molecules-controlled spontaneous growth of Se crystals with roselike and orchidslike shapes at
Luminescence and defect studies of Ce3+ doped CaS phosphor synthesized via solid state diffusion met
Luminescence and EPR investigations of Mn activated calcium aluminate prepared via combustion method
Theoretical investigation on conformational behavior of 2,2’-bithiophene under the influence of exte
First-principles study of substituents effect on molecular junctions: Towards molecular rectificatio
Determination of polymerization retarder 4-hydroxyanisole in triallyl cyanurate for industrial use b
Determination of silymarin flavonoids by HPLC and LC-MS, and investigation of extraction rate of sil
Three-Dimensionally Ordered Macroporous Gold Structure as an efficient matrix for Solid State Electr
Glucose microfluidic biosensors based on immobilizing glucose oxidase in poly(dimethylsiloxane) elec
Off-line form of the Michaelis-Menten equation for studying the enzyme kinetics in a polymer microch
Indirect amperometric measurement of electroosmotic flow rates and effective mobilities in microchip
Synthesis of functional polypyrrole/prussian blue and polypyrrole/Ag composite microtubes by using a
Ordered mesoporous polyaniline film as a new matrix for enzyme immobilization and biosensor construc
Hb-CdTe-CaCO3@Polyelectrolytes 3D Architecture: Fabrication, Characteri- zation and Application in B
Synthesis, photoluminescence, thermoluminescence and electron spin resonance investigations of CaAl1
Theoretical investigations of oligo(phenylene ethylene) molecular wire: effects from substituents an
Sonochemical synthesis and resonance light scattering effect of Zn(II)bis(1-(2-pyridylazo)-2-naphtho
Direct electron transfer and biosensing application of proteins immobilized on NaY zeolite and mesop
Coupling imaging mode to investigate the electric field distribution at the end-channel of capillary
A Simple Electrochemical Method for the Detection of Hydroxyl Free Radicals without Separation Proce
Zirconia nanoparticles enhanced grafted collagen tri-helix scaffolds for unmediated biosensing of hy
Luminescent CdS nanochains templated on unfixed DNA and their fractal alignment by droplet dewetting
Flow-through multianalyte chemiluminescent immunosensing system with designed substrate zone-resolve
Dynamic kinetic capillary isoelectric focusing: a powerful tool for studying protein-DNA interaction
Aminopolycarboxyl-modified Ag2S nanoparticles: Synthesis, characterization and resonance light scatt
Antimony(III)-doped PbWO4 crystals with enhanced photoluminescence via a shape-controlled sonochemic
Silver/silver oxide-silicon dioxide nanoparticles modified electrodes for electrochemical sensing of
Determination of heterocyclic amines by capillary electrophoresis with UV-DAD detection using on-lin
Sonochemical route for self-assembled V2O5 bundles with spindle-like morphology and their novel appl
Ag/polypyrrole core-shell nanostructures: Interface polymerization, characterization, and modificati
Sampling-resolution strategy for one-way multiplexed immunoassay with sequential chemiluminescent de
Conductive mesocellular silicate- carbon nanocomposite foams for immobilization, direct electrochemi
Simultaneous determination of psychoactive drugs in human urine by capillary electrophoresis with el
A disposable and reagentless electrochemical immunosensor array based on a biopolymer/sol-gel membra
A disposable multianalyte electrochemical immunosensors array for automated simultaneous determinati
Controllable synthesis of one-dimensional chinelike superstructures of homogeneous Bi100-xSbx alloys
Simultaneous electrochemilumines- cence detection of anisodamine, atropine and scopolamine in Flos D
Electrodeposition of silver-DNA hybrid nanoparticles for electrochemical sensing of hydrogen peroxid
A biocompatible conductive architecture of carbon nanofiber-doped chitosan prepared with controllabl
Electric field-driven strategy for fast multiplexed detection of protein biomarkers using a disposab
Highly sensitive amperometric determination of carbohydrates with a portable silicone/quartz capilla
Effective cell capture with tetrapeptide functionalized carbon nanotubes and dual signal amplificati
Coreactant enhanced anodic electrochemiluminescence of CdTe quantum dots at low potential for sensit
Preparation, luminescence and defect studies of Eu2+-activated strontium hexa-aluminate phosphor pre
High efficient separation and electrochemical detection of neurotransmitters on a native printed cap
Liquid chromatographic fingerprint of 3-methylflavone-8-carboxylic acid established for its synthesi
Novel C-Au ligand mechanism for the synthesis of super stable n-trimethyl chitosan chloride derivati
Direct electron transfer and electrocatalysis of hemoglobin adsorbed on mesoporous carbon through la
An unusual metabolite of cimicidol-3- O-β-D-xyloside from Cimicifugae rhizoma by rat intestinal bact
Nano-pit corrosion of the tabs in aluminum electrolytic capacitor: Polarization characteristics of t
Al2O3/SnO2 co-nanoparticle modified grafted collagen for improving thermal stability and infrared em
Direct electrochemistry and electrocatalysis of hemoglobin in gelatine film modified glassy carbon e
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